Research ArticleAsian Journal of Biological and Life SciencesVol. 11 | Issue 1 | pp. 166–172Open access
Cytotoxicity, Antioxidant Activity, and Total Phenolic Content of the Ethanolic Leaf Extract of Hornstedtia conoidea Ridl
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- 1 Department of Chemistry, Central Mindanao University, University Town, Musuan, Bukidnon, PHILIPPINES.
Published in Asian Journal of Biological and Life Sciences
Correspondence: Gina Barbosa Barbosa
Department of Chemistry, Central Mindanao University, University Town, Musuan, Bukidnon, PHILIPPINES.
Email: ginavbatoy@yahoo.com
- Received:
- Feb 27, 2022
- Accepted:
- Apr 5, 2022
- DOI:
- 10.5530/ajbls.2022.11.23
How to cite
Barbosa, G. B., Alinapon, C. V., Enot, M. M., Baltazar, G. J. D., Buncales, E. O., Gultiano, A. G., & Ang, A. M. G. Cytotoxicity, Antioxidant Activity, and Total Phenolic Content of the Ethanolic Leaf Extract of Hornstedtia conoidea Ridl. Asian Journal of Biological and Life Sciences, 11(1), 166–172. https://doi.org/10.5530/ajbls.2022.11.23
Abstract
This study uncovers the potential benefits of the leaves of the less explored Philippine endemic Hornstedtia conoidea. This study aimed to determine the total phenolic content (TPC), total flavonoid content (TFC), total antioxidant activity (TAA), and cytotoxicity of the ethanolic leaf extract of the H. conoidea. TPC, TFC, and TAA were determined using the Folin-Ciocalteu method, aluminum chloride method, and phosphomolybdenum method, respectively. Cytotoxicity was determined via brine shrimp lethality assay (BSLA). The TPC, TFC, and TAA of the extract were 13.29 ± 0.32, 6.87 ± 0.26, and 261.60 ± 6.06 mg/g dry sample, respectively. The extract exhibited toxicity with LC50 of 24.61 mg/L based on BSLA. Ethanolic leaf extract of H. conoidea possesses antioxidative activity and cytotoxic properties.
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Article metadata
| Title | Cytotoxicity, Antioxidant Activity, and Total Phenolic Content of the Ethanolic Leaf Extract of Hornstedtia conoidea Ridl |
|---|---|
| Authors | Gina Barbosa Barbosa; Cresilda Vergara Alinapon; Melania Manginsay Enot; Gloria Jesusa Detecio Baltazar; Emma Orbita Buncales; Analyn Galo Gultiano; Aileen May Gabule Ang |
| Affiliations | Department of Chemistry, Central Mindanao University, University Town, Musuan, Bukidnon, PHILIPPINES. |
| Corresponding author | ginavbatoy@yahoo.com |
| Journal | Asian Journal of Biological and Life Sciences |
| Volume / Issue | Vol. 11, Issue 1 |
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