research-articleAsian Journal of Biological and Life SciencesVol. 14 | Issue 1 | 2025 | pp. 18–22Open access
The Challenges and Novel Approaches in the Nanoparticle Formulation of DPP Inhibitors
- 1*,
- 1*,
- 2*,
- 3*
- 1 Department of Pharmaceutics, School of Pharmacy, Sri Balaji Vidyapeeth (Deemed to be University), Puducherry Campus, Puducherry, Tamil Nadu, India.
- 2 Department of Biotechnology, Faculty of Medicine and Bioscience, MAHSA University, Bandar Saujana Putra, Jenjarom, Selangor Darul Ehsan, Malaysia.
- 3 Department of Biotechnology, Faculty of Pharmacy, Lincoln University, Petaling Jaya, Sunway City, Malaysia.
Published in Asian Journal of Biological and Life Sciences
Correspondence: Jaganathan Saravanan
Department of Pharmaceutics, School of Pharmacy, Sri Balaji Vidyapeeth (Deemed to be University), Puducherry Campus, Puducherry, Tamil Nadu, India.
Email: revathis79@gmail.com
Copyright: © 2025 Manuscript Technomedia. This is an open access article.
- Published:
- Jan 1, 2025
- Received:
- Jan 3, 2025
- Accepted:
- Mar 18, 2025
- DOI:
- 10.5530/ajbls.20251309
How to cite
Saravanan, J., Revathi, S., Ponnaiah, P., & Eden, V. R. (2025). The Challenges and Novel Approaches in the Nanoparticle Formulation of DPP Inhibitors. Asian Journal of Biological and Life Sciences, 14(1), 18–22. https://doi.org/10.5530/ajbls.20251309
Abstract
Drug delivery methods based on nanoparticles have shown great promise in the effective administration of medicinal drugs, such as inhibitors of Dipeptidyl Peptidase (DPP). In the treatment of type 2 diabetes, DPP inhibitors are commonly used, and their formulation as nanoparticles offers numerous advantages, such as enhanced bioavailability, controlled release, and targeted delivery. However, several challenges exist in formulating DPP inhibitors into nanoparticles, including drug stability, particle size control, and sustained release kinetics. This review article aims to discuss the challenges associated with nanoparticle formulation of DPP inhibitors and highlight recent innovative approaches to overcome these limitations.
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Article metadata
| Title | The Challenges and Novel Approaches in the Nanoparticle Formulation of DPP Inhibitors |
|---|---|
| Authors | Jaganathan Saravanan; Sundaramoorthi Revathi; Paulraj Ponnaiah; Vitalis Ronald Eden |
| Affiliations | Department of Pharmaceutics, School of Pharmacy, Sri Balaji Vidyapeeth (Deemed to be University), Puducherry Campus, Puducherry, Tamil Nadu, India.; Department of Biotechnology, Faculty of Medicine and Bioscience, MAHSA University, Bandar Saujana Putra, Jenjarom, Selangor Darul Ehsan, Malaysia.; Department of Biotechnology, Faculty of Pharmacy, Lincoln University, Petaling Jaya, Sunway City, Malaysia. |
| Corresponding author | revathis79@gmail.com |
| Journal | Asian Journal of Biological and Life Sciences |
| Volume / Issue | Vol. 14, Issue 1 (2025) |
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