research-articleAsian Journal of Biological and Life SciencesVol. 14 | Issue 2 | 2025 | pp. 400–409Open access
Identification of Hub Genes and Therapeutic Targets in Lung Cancer Using Software Tools
- 1*,
- 1
- 1 Department of Biotechnology, Bharath Institute of Higher Education and Research, Chennai, Tamil Nadu, INDIA.
Published in Asian Journal of Biological and Life Sciences
Correspondence: S. Anbuselvi
Department of Biotechnology, Bharath Institute of Higher Education and Research, Chennai, Tamil Nadu, INDIA.
Email: drsanbuselvi@gmail.com
Copyright: © 2025 Manuscript Technomedia. This is an open access article.
- Published:
- Jan 1, 2025
- Received:
- Feb 12, 2025
- Accepted:
- Jun 27, 2025
- DOI:
- 10.5530/ajbls.20251509
How to cite
Anbuselvi, S., & Saranya, S. (2025). Identification of Hub Genes and Therapeutic Targets in Lung Cancer Using Software Tools. Asian Journal of Biological and Life Sciences, 14(2), 400–409. https://doi.org/10.5530/ajbls.20251509
Abstract
Background: Lung cancer remains a leading cause of cancer deaths. Objective: Identify hub genes associated with lung cancer via GEO curation and PPI/network analyses to prioritize therapeutic targets. Methods: Functional enrichment (DAVID, ShinyGO), druggability assessment (ChEMBL, Pharos). Results: Top hub genes and enriched pathways reported; chemokine receptor activity and T-cell receptor related functions highlighted. Conclusion: Prioritized hub genes provide resources for experimental validation.
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Article metadata
| Title | Identification of Hub Genes and Therapeutic Targets in Lung Cancer Using Software Tools |
|---|---|
| Authors | S. Anbuselvi; S. Saranya |
| Affiliations | Department of Biotechnology, Bharath Institute of Higher Education and Research, Chennai, Tamil Nadu, INDIA. |
| Corresponding author | drsanbuselvi@gmail.com |
| Journal | Asian Journal of Biological and Life Sciences |
| Volume / Issue | Vol. 14, Issue 2 (2025) |
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