Case ReportAsian Journal of Biological and Life SciencesVol. 9 | Issue 3 | 2020 | pp. 421–423Open access
Double Chromosomal Anomalies in Turner Syndrome: Rare Co-existence of Robertsonian Translocation with Monosomy X and Isochromosome XQ
- 1,
- 1*
- 1 Department of Genetics, Thyrocare Technologies Limited, Plot No.D37/1, TTC Industrial area, MIDC, Turbhe, Navi Mumbai, Maharashtra, INDIA.
Published in Asian Journal of Biological and Life Sciences
Correspondence: Sandhya Iyer
Department of Genetics, Thyrocare Technologies Limited, Plot No.D37/1, TTC Industrial area, MIDC, Turbhe, Navi Mumbai, Maharashtra, INDIA.
Email: sandhya.iyer@thyrocare.com
Copyright: © 2020 Manuscript Technomedia. This is an open access article.
- Published:
- Dec 30, 2020
- Received:
- Sep 17, 2020
- Accepted:
- Dec 2, 2020
- DOI:
- 10.5530/ajbls.2020.9.64
How to cite
Sinkar, P., & Iyer, S. (2020). Double Chromosomal Anomalies in Turner Syndrome: Rare Co-existence of Robertsonian Translocation with Monosomy X and Isochromosome XQ. Asian Journal of Biological and Life Sciences, 9(3), 421–423. https://doi.org/10.5530/ajbls.2020.9.64
Abstract
Background and Aim:The co-existence of a Robertsonian translocation with Turner Syndrome (TS) or variant of Turner Syndrome (isochromosome Xq) is an uncommon phenomenon. In this report we present two cases with double chromosomal anomalies.Case Report:In the first case, we present findings from a 19 years old female, detected to harbor classic TS combined with t(13;14) Robertsonian translocation. The second case involves a 13 years old female, with isochromosome Xq10 (a known variant of Turner Syndrome) combined with t(13;14) Robertsonian translocation.Conclusion:Literature around double chromosome anomalies were found to be few and our case report is one of the first few to identify structural abnormality of X chromosome (isochromosome X) along with a t(13;14) Robertsonian translocation.
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Article metadata
| Title | Double Chromosomal Anomalies in Turner Syndrome: Rare Co-existence of Robertsonian Translocation with Monosomy X and Isochromosome XQ |
|---|---|
| Authors | Prachi Sinkar; Sandhya Iyer |
| Affiliations | Department of Genetics, Thyrocare Technologies Limited, Plot No.D37/1, TTC Industrial area, MIDC, Turbhe, Navi Mumbai, Maharashtra, INDIA. |
| Corresponding author | sandhya.iyer@thyrocare.com |
| Journal | Asian Journal of Biological and Life Sciences |
| Volume / Issue | Vol. 9, Issue 3 (2020) |
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