Case SeriesIndian Journal of Pharmacy PracticeVol. 10 | Issue 2 | pp. 142–146Open access
Isoniazid Associated Psychosis: A Case Series of 3 Patients
- 1*,
- 2,
- 3,
- 4,
- 5
- 1 Doctoral Research Scholar, Department of Pharmacy Practice, JSS College of Pharmacy, JSS University, Mysore- 15, Karnataka, INDIA.
- 2 Pharm.D Intern, Department of Pharmacy Practice, JSS College of Pharmacy, JSS University, Mysore- 15, Karnataka, INDIA.
- 3 Associate Professor, Department of General Medicine, JSS Medical College & Hospital, JSS University, Mysore- 15, Karnataka, INDIA.
- 4 Associate Professor, Department of General Medicine, JSS Medical College & Hospital, JSS University, Mysore- 15, Karnataka, INDIA.
- 5 Professor and Head, Department of Pharmacy Practice, JSS College of Pharmacy, JSS University, Mysore- 15, Karnataka, INDIA.
Published in Indian Journal of Pharmacy Practice
Correspondence: Vineetha Bharathan Menon
Doctoral Research Scholar, Department of Pharmacy Practice, JSS College of Pharmacy, JSS University, Mysore- 15, Karnataka, INDIA.
Email: vineethamenon54@yahoo.com
- DOI:
- 10.5530/ijopp.10.2.29
How to cite
Menon, V. B., Shaji, R., Pereira, P., Chikkaveeraiah, S. K., & Ramesh, M. Isoniazid Associated Psychosis: A Case Series of 3 Patients. Indian Journal of Pharmacy Practice, 10(2), 142–146. https://doi.org/10.5530/ijopp.10.2.29
Abstract
Background: Isoniazid is the first line agent for the treatment of tuberculosis. Psychosis is a known complication of isoniazid therapy, although infrequent. Case report: One female and two male patients aged 35 years, 55 years and 60 years respectively developed psychosis following isoniazid administration. All the three received 300 mg of isoniazid daily for the management of pulmonary tuberculosis. High dose of isoniazid and low body mass index were identified as the common risk factor for the development of isoniazid associated psychosis. The incidence, possible pathogenesis, risk factors and treatment options are discussed. Conclusion: Isoniazid psychosis is a major complication, which if recognized early can be effectively treated.
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Article metadata
| Title | Isoniazid Associated Psychosis: A Case Series of 3 Patients |
|---|---|
| Authors | Vineetha Bharathan Menon; Rinu Shaji; Pratibha Pereira; Shashidhara Kuppegala Chikkaveeraiah; Madhan Ramesh |
| Affiliations | Doctoral Research Scholar, Department of Pharmacy Practice, JSS College of Pharmacy, JSS University, Mysore- 15, Karnataka, INDIA.; Pharm.D Intern, Department of Pharmacy Practice, JSS College of Pharmacy, JSS University, Mysore- 15, Karnataka, INDIA.; Associate Professor, Department of General Medicine, JSS Medical College & Hospital, JSS University, Mysore- 15, Karnataka, INDIA.; Associate Professor, Department of General Medicine, JSS Medical College & Hospital, JSS University, Mysore- 15, Karnataka, INDIA.; Professor and Head, Department of Pharmacy Practice, JSS College of Pharmacy, JSS University, Mysore- 15, Karnataka, INDIA. |
| Corresponding author | vineethamenon54@yahoo.com |
| Journal | Indian Journal of Pharmacy Practice |
| Volume / Issue | Vol. 10, Issue 2 |
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