Original ArticleIndian Journal of Pharmaceutical Education and ResearchVol. 53 | Issue 4s | 2019 | pp. s678–s683Open access
Cassia auriculata L.: An Ethno Medical Approach in Exploring Anti-solar Efficacy
- *,
- ,
- ,
- 1 Department of Pharmaceutical Chemistry, KLES’s College of Pharmacy, Nipani, Karnataka, INDIA.
- 2 Department of Pharmaceutics, KLES’s College of Pharmacy, Nipani, Karnataka, INDIA.
Published in Indian Journal of Pharmaceutical Education and Research
Correspondence: Krantisinha Hanumant Randive
Copyright: © 2019 Manuscript Technomedia. This is an open access article.
- Published:
- Jan 1, 2019
- Received:
- Mar 16, 2019
- Accepted:
- Jul 20, 2019
- DOI:
- 10.5530/ijper.53.4s.164
How to cite
Randive, K. H., Hiremath, R. D., Kempwade, A. A., & Patil, A. A. (2019). Cassia auriculata L.: An Ethno Medical Approach in Exploring Anti-solar Efficacy. Indian Journal of Pharmaceutical Education and Research, 53(4s), s678–s683. https://doi.org/10.5530/ijper.53.4s.164
Abstract
Objectives: The present study deals with an in-vitro screening for the anti-solar potential of aqueous and ethanolic extracts of Cassia auriculata using the UV method. Methods: Aqueous and ethanolic extracts were prepared. Thus, prepared extracts were subjected to phytochemical investigation and evaluated for antioxidant effect using DPPH and antisolar efficacy. Concentrations ranging from 7.8 to 1000 μg/mL (serial dilution) were used for the determination of radical scavenging effect and concentration of 2 mg/mL was used for screening of anti-solar potential using Shimadzu UV-1700 double beam UV-Visible spectrophotometer. Readings were recorded in triplicate and graphs were extrapolated. Results: Extracts revealed the presence of important phytoconstituents such as phenols, triterpenoids, flavonoids, tannins, saponins, phytosterols, alkaloids and glycosides. Further, it was observed that Cassia auriculata possesses remarkable antioxidant activity. Significant results of the anti-solar screening study confirm its use as a natural sunscreen. It showed a protective effect against carcinogenic UV radiation. Ethanolic extract was found to be more effective in comparison with aqueous extract. Conclusion: From the data, it can be concluded that aqueous and ethanolic extracts showed promising antioxidant and anti-solar activity which could be considered as a rational alternative to chemically prepared synthetic sunscreen formulations available in the market.
Keywords
Subject
Article metadata
| Title | Cassia auriculata L.: An Ethno Medical Approach in Exploring Anti-solar Efficacy |
|---|---|
| Authors | Krantisinha Hanumant Randive; Ravindra Durdundayya Hiremath; Amolkumar Ashok Kempwade; Anagha Ashok Patil |
| Affiliations | Department of Pharmaceutical Chemistry, KLES’s College of Pharmacy, Nipani, Karnataka, INDIA.; Department of Pharmaceutics, KLES’s College of Pharmacy, Nipani, Karnataka, INDIA. |
| Journal | Indian Journal of Pharmaceutical Education and Research |
| Volume / Issue | Vol. 53, Issue 4s (2019) |
Also in this issue
- New Drugs and Clinical Trials Rules, 2019: Towards Fast-track Accessibility of New Drugs to the Indian Populationpp. s451–s459
- Improved Method for Differentiation of Synthetic and Natural Endogenous Anabolic Steroids using Gas Chromatography Isotope Ratio Mass Spectrometry (GC/C/IRMS) followed by Two-Fold High Performance Liquid Chromatography (HPLC) Cleanup Method: A Perspectivepp. s460–s465
- A Review on Complications Confronted with Skin Penetration and Assessment of Topical Formulations in Dermal Drug Developmentpp. s466–s474
- Recent Advancements in Spectrophotometric pKa Determinations: A Reviewpp. s475–s480
- Therapeutic Proteins through Phage Display- A Brilliant Technique for its Simplicitypp. s481–s486