Original ArticleIndian Journal of Pharmaceutical Education and ResearchVol. 57 | Issue 3s | 2023 | pp. s710–s717Open access
In vitro and in vivo Antidiabetic Activity of Ag Nanoparticles Mediated from Gymnemic Acid I and II
- 1,
- 1*
- 1 Department of Pharmacognosy, JSS College of Pharmacy, Ooty, Nilgiris, Tamil Nadu, INDIA.
Published in Indian Journal of Pharmaceutical Education and Research
Correspondence: Kalakotla Shanker
Department of Pharmacognosy, JSS College of Pharmacy, Ooty, Nilgiris, Tamil Nadu, INDIA.
Email: shankerkalakotla@gmail.com
Copyright: © 2023 Manuscript Technomedia. This is an open access article.
- Published:
- Jan 1, 2023
- Received:
- Aug 27, 2022
- Accepted:
- Jun 8, 2023
- DOI:
- 10.5530/ijper.57.3s.80
How to cite
Sivaramakumar, N., & Shanker, K. (2023). In vitro and in vivo Antidiabetic Activity of Ag Nanoparticles Mediated from Gymnemic Acid I and II. Indian Journal of Pharmaceutical Education and Research, 57(3s), s710–s717. https://doi.org/10.5530/ijper.57.3s.80
Abstract
Background: Gymnema sylvestre is traditionally used to treat diabetes in Asia. Materials and methods: GA-I and GA-II were docked to PTP 1B. Nanoparticles were produced using centrifugation green synthesis. Results: Blood glucose levels significantly decreased (p less than 0.001) at a dose of 200 mg/kg of GA-I mediated AgNPs. Conclusion: GA-I mediated AgNPs can be exploited as prospective nanomedicine for type-2 diabetes.
Keywords
Article metadata
| Title | In vitro and in vivo Antidiabetic Activity of Ag Nanoparticles Mediated from Gymnemic Acid I and II |
|---|---|
| Authors | Navanita Sivaramakumar; Kalakotla Shanker |
| Affiliations | Department of Pharmacognosy, JSS College of Pharmacy, Ooty, Nilgiris, Tamil Nadu, INDIA. |
| Corresponding author | shankerkalakotla@gmail.com |
| Journal | Indian Journal of Pharmaceutical Education and Research |
| Volume / Issue | Vol. 57, Issue 3s (2023) |
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