research-articleIndian Journal of Pharmaceutical Education and ResearchVol. 58 | Issue 2s | 2024 | pp. s340–s353Open access
Effectiveness of Complementary and Alternative Medicine and Physical Therapies in Peripheral Arterial Disease with Intermittent Claudication: A Systematic Review
- 1*,
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- 1 Department of Clinical Pharmacy, King Fahad Medical City, Riyadh, SAUDI ARABIA.
- 2 Department of Cardiac Science, College of Medicine, King Saud University, Riyadh, SAUDI ARABIA.
- 3 Department of Pharmacy, Maternity and Children Hospital Rafah, Rafha, SAUDI ARABIA.
- 4 Department of Clinical Pharmacy, Western Zone, Taif, SAUDI ARABIA.
- 5 Department of Community Pharmacy, Kol Alosra, Western Zone, Taif, SAUDI ARABIA.
- 6 Department of Pharmacy, Prince Sultan Cardiac Center, Riyadh, SAUDI ARABIA.
- 7 College of Pharmacy, Northern Border University, Hafar Al-Batin, SAUDI ARABIA.
- 8 College of Clinical Pharmacy, Imam Abdulrahman Bin Faisal University, SAUDI ARABIA.
- 9 College of Pharmacy, Northern Border University, Rafha, SAUDI ARABIA
- 10 College of Clinical Pharmacy, Imam Abdulrahman Bin Faisal University, Dammam, SAUDI ARABIA.
Published in Indian Journal of Pharmaceutical Education and Research
Correspondence: Mohammed Kanan Alshammari
Department of Clinical Pharmacy, King Fahad Medical City, Riyadh, SAUDI ARABIA.
Email: ii_kanan101@outlook.com
Copyright: © 2024 Manuscript Technomedia. This is an open access article.
- Published:
- Jan 1, 2024
- Received:
- Jul 3, 2023
- Accepted:
- Jan 19, 2024
- DOI:
- 10.5530/ijper.58.2s.37
How to cite
Alshammari, M. K., Hussain, K. H., Alshammari, M. R., Alshammari, H. H., Althagafi, H. S., Bajunaid, H. R., Alanzi, B. A., Alshammari, A. A., Alshammari, A. K., Aljasim, M. A. J., Alanizi, Y. S., Al-Sulais, W. M., & Albaqami, A. A. A. N. D. (2024). Effectiveness of Complementary and Alternative Medicine and Physical Therapies in Peripheral Arterial Disease with Intermittent Claudication: A Systematic Review. Indian Journal of Pharmaceutical Education and Research, 58(2s), s340–s353. https://doi.org/10.5530/ijper.58.2s.37
Abstract
Aim/Background
Peripheral Arterial Disease (PAD) affects the lower limbs. Globally there is a growing disease burden among the patients suffering from cardio-vascular disease and metabolic disorders. The purpose of this review is to generate evidence on the efficacy of CAM therapies in PAD.
Materials and Methods
This systematic review was performed across the five electronic databases i.e. PubMed, Cochrane Central Register of Controlled Trials (CENTRAL), Ovid SP, ISI Web of Science, Elsevier Science Direct, and Wiley Online Library as per the PRISMA guidelines from inception till April 2022.
Results
After screening n=55,410 articles, n=77 articles were found to fulfill the eligibility criteria and were selected for this review. The nature of interventions investigated in the clinical trials were physical interventions including exercises of different forms, oral supplements, and other interventions such as chelation therapy, Tai Chi Chuan (TCC), Intermittent Mechanical Compression (IMC) device, connective tissue reflex massage, Remote Ischemic Preconditioning (RIC), Transcutaneous Electrical Nerve Stimulation (TENS) and heat therapy. Upon final assessment, it was revealed that physical activity had a positive effect on peripheral arterial disease patients’ quality of life. In addition,Ginkgo biloba and nitrate supplements were found effective for Intermittent Claudication (IC) and PAD patients.
Conclusion
This review suggests a positive impact of physical activity on peripheral arterial disease patients’ quality of life. Evidence also shows that Physical activity/ exercise-based intervention alone or in combination with the supplement is found to be effective among PAD patients and has shown significant results in intermittent claudication.
Keywords
Subject
Article metadata
| Title | Effectiveness of Complementary and Alternative Medicine and Physical Therapies in Peripheral Arterial Disease with Intermittent Claudication: A Systematic Review |
|---|---|
| Authors | Mohammed Kanan Alshammari; Khansa Hamza Hussain; Maali Ramadan Alshammari; Hanan Haif Alshammari; Hadeel Saad Althagafi; Hanan Rashad Bajunaid; Bashayr Abdullah Alanzi; Abdullah Ayed Alshammari; Abdulaziz Khalaf Alshammari; Mujtaba Abbas Jasim Aljasim; Yazeed Saud Alanizi; Wala’a Mohammed Al-Sulais; Ahad Aref Alsulays Nashi Dukhi Albaqami |
| Affiliations | Department of Clinical Pharmacy, King Fahad Medical City, Riyadh, SAUDI ARABIA.; Department of Cardiac Science, College of Medicine, King Saud University, Riyadh, SAUDI ARABIA.; Department of Pharmacy, Maternity and Children Hospital Rafah, Rafha, SAUDI ARABIA.; Department of Clinical Pharmacy, Western Zone, Taif, SAUDI ARABIA.; Department of Community Pharmacy, Kol Alosra, Western Zone, Taif, SAUDI ARABIA.; Department of Pharmacy, Prince Sultan Cardiac Center, Riyadh, SAUDI ARABIA.; College of Pharmacy, Northern Border University, Hafar Al-Batin, SAUDI ARABIA.; College of Clinical Pharmacy, Imam Abdulrahman Bin Faisal University, SAUDI ARABIA.; College of Pharmacy, Northern Border University, Rafha, SAUDI ARABIA; College of Clinical Pharmacy, Imam Abdulrahman Bin Faisal University, Dammam, SAUDI ARABIA. |
| Corresponding author | ii_kanan101@outlook.com |
| Journal | Indian Journal of Pharmaceutical Education and Research |
| Volume / Issue | Vol. 58, Issue 2s (2024) |
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