Review ArticleIndian Journal of Pharmaceutical Education and ResearchVol. 59 | Issue 2s | 2025 | pp. s399–s409Open access
Casting a Spotlight on Factorial Design: Exploring the Power of DoE for Experiment Screening and Optimization: A Mini Review
- 1*,
- 2*,
- 3*
- 1 Department of Pharmaceutical Sciences, Vignan’s Foundation for Science, Technology and Research (Deemed to be University),Guntur, Andhra Pradesh, India.
- 2 Department of Pharmaceutical Analysis, Dr. Kalam College of Pharmacy, Avanam, ThanjavurTamil Nadu, INDIA., Tamil Nadu, India.
- 3 Department of Pharmaceutics, Narasaraopeta Institute of Pharmaceutical Sciences (Autonomous), Narasaraopet, Palnadu, Andhra Pradesh, INDIA.
Published in Indian Journal of Pharmaceutical Education and Research
Correspondence: Prathap Madeswara Guptha
Department of Pharmaceutical Sciences, Vignan’s Foundation for Science, Technology and Research (Deemed to be University),Guntur, Andhra Pradesh, India.
Email: vijaysurender85@gmail.com
Copyright: © 2025 Manuscript Technomedia. This is an open access article.
- Published:
- Jan 1, 2025
- Received:
- May 25, 2024
- Accepted:
- Jan 9, 2025
- DOI:
- 10.5530/ijper.20256017
How to cite
Guptha, P. M., Surendran, V., & Gunda, R. K. (2025). Casting a Spotlight on Factorial Design: Exploring the Power of DoE for Experiment Screening and Optimization: A Mini Review. Indian Journal of Pharmaceutical Education and Research, 59(2s), s399–s409. https://doi.org/10.5530/ijper.20256017
Abstract
ABSTRACT
Design of Experiments (DOE) is a powerful and systematic approach used in various fields to efficiently plan, execute and analyze experiments. This review provides a comprehensive overview of the application of DOE in the context of screening and optimization of experiments. Screening experiments are employed to identify significant factors or variables that influence a response, while optimization experiments aim to fine-tune these factors to achieve optimal outcomes. The review introduces the fundamental concepts of DOE, including factors, levels and response variables. It explores the various types of designs commonly used in screening, such as full factorial, Taguchi and Plackett-Burman designs, highlighting their advantages and limitations. The article also delves into the practical aspects of designing and conducting experiments with DOE, emphasizing the importance of proper planning and statistical analysis. Key topics covered include the selection of appropriate designs, sample size determination and data analysis techniques. Furthermore, the review touches upon the integration of computer-aided tools and software for DOE, making the process more efficient and accessible. The review also discusses the impact of DOE on resource and time savings, as well as its potential for enhancing product quality and process efficiency. This review underlines the significance of Design of Experiments in screening and optimization, offering insights into its versatility, practical implementation and the substantial benefits it can bring to research and industry. Researchers, practitioners and decision-makers in various domains will find this review valuable in harnessing the full potential of DOE for improving experimentation and decision-making processes.
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Article metadata
| Title | Casting a Spotlight on Factorial Design: Exploring the Power of DoE for Experiment Screening and Optimization: A Mini Review |
|---|---|
| Authors | Prathap Madeswara Guptha; Vijayaraj Surendran; Raghavendra Kumar Gunda |
| Affiliations | Department of Pharmaceutical Sciences, Vignan’s Foundation for Science, Technology and Research (Deemed to be University),Guntur, Andhra Pradesh, India.; Department of Pharmaceutical Analysis, Dr. Kalam College of Pharmacy, Avanam, ThanjavurTamil Nadu, INDIA., Tamil Nadu, India.; Department of Pharmaceutics, Narasaraopeta Institute of Pharmaceutical Sciences (Autonomous), Narasaraopet, Palnadu, Andhra Pradesh, INDIA. |
| Corresponding author | vijaysurender85@gmail.com |
| Journal | Indian Journal of Pharmaceutical Education and Research |
| Volume / Issue | Vol. 59, Issue 2s (2025) |
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