Volume 59
Volume 59, Issue 4
Review Article
The Construction and Application of Process Evaluation in the Grade Evaluation of Pharmacology Experiment
Hua Li, Lin Liu, Mao Li, Yuhong Sun, Minghua Liu
Vol. 59 · Issue 4 · pp. 1238–1244
Review Article
Navigating USFDA Inspectional Observations: An Analysis of Trends and Compliance from Fiscal Years 2019 To 2022
Antony Sebastian Johnson, Balamuralidhara Veeranna, Saba Maanvizhi
Vol. 59 · Issue 4 · pp. 1245–1253
Review Article
Enhancing Lyophilization Efficiency: A Review of Processes, Parameters and Product Preservation Strategies
Dhakane Sumeet, Jain Rahul, Joshi Neeta
Vol. 59 · Issue 4 · pp. 1254–1261
Review Article
Nose-to-Brain Drug Delivery: An Update on Clinical Challenges and Progress
Purushottam Gangane, Nikita Raulkar, Nikita Wagh, Vijaya Rabade, Harigopal Sawarkar
Vol. 59 · Issue 4 · pp. 1262–1271
Original Article
Students' Perception of the “Two-Stage” Collaborative Examination Based on the Focus Group Interview Method
Li Ming Wang, Yan Chun Wang, Shan Shan Li, Ying Jin
Vol. 59 · Issue 4 · pp. 1272–1276
Original Article
Investigate of the Relationship between Thinking Styles and Classroom Management of the Teachers of Vocational Colleges
Weiguo Hu, Zi Ye, Chou Chen, Wei Chen, Chan Li, Haijun Zhou, Ruiyang Chen
Vol. 59 · Issue 4 · pp. 1277–1284
Original Article
Screening and Optimization of Various Formulation and Processing Parameters for the Development of Aquasomes
Khushboo Katharotiya, Dhaval Katharotiya, Lalit Lata Jha
Vol. 59 · Issue 4 · pp. 1285–1292
Original Article
Co-Delivery of Sphingosomal Formulation Containing BCL2 siRNA Doxorubicin for the Treatment of Lung Cancer
Prashant Nayak, Rompicherla Narayana Charyulu
Vol. 59 · Issue 4 · pp. 1293–1304
Original Article
Formulation, Optimization and Evaluation of Naringenin Loaded Cubosomes for Effective Management of Alzheimer's Disease
Yashowardhan Raut, Kishori Prasanna Sutar, Shivaraj Hooli, Gautam Naik, Vinayak Udagatti
Vol. 59 · Issue 4 · pp. 1305–1311
Original Article
Formulation and Evaluation of Propolis Loaded Nanosponges Based Topical Anti-Inflammatory Gel
Mukesh P. Ratnaparkhi, Swati Dattatray Kshirsagar
Vol. 59 · Issue 4 · pp. 1312–1322
Original Article
Formulation Development and Evaluation of Iloperidone Loaded Nanosuspension for Solubility Enhancement
Shivraj Popat Jadhav, Prashant Kumar Dhakad, Tapasvi Gupta, Ritu Gilhotra
Vol. 59 · Issue 4 · pp. 1323–1333
Original Article
Antioxidant Assessment of Albizia lebbeck SLNs
S K Kavitha, Ali Mohammad, Bharathi D R, Yogesh H S
Vol. 59 · Issue 4 · pp. 1334–1346
Original Article
Repurposing Efavirenz for Anticancer Therapy with Curcumin Combination in Solid Lipid Nanoparticle Formulation
Mani Uppada, Srinivasa Rao Yarraguntla, Sai Sri Vastav Mylavarapu, Persis Joni Kappala, Satyalakshmi Siragam
Vol. 59 · Issue 4 · pp. 1347–1356
Original Article
Development and Optimization of Novel Microwave-Assisted Extraction for Rich-Flavonoids and Polyphenols from Dioscorea bulbifera Leaves by Response Surface Methodology
Soma Uday Kumar Reddy, Divya Jyothi, Krishna Kana Veetil, Shreya Shreya, Rokeya Sultana, Sneh Priya
Vol. 59 · Issue 4 · pp. 1357–1365
Original Article
Anti-inflammatory and Anti-allergic Effects of Salvigenin in an Ovalbumin-Induced Allergic Rhinitis in Mice
Nan Gong, Huimin Chang, Mengchao He, Xiaohong Zhang, Wenjing Li
Vol. 59 · Issue 4 · pp. 1366–1374
Original Article
Herniarin Alleviates Lipopolysaccharide-Induced Acute Lung Injury in Mice via Regulating Oxidative Stress, Inflammation and Apoptosis Mechanisms
Li Jiang, Tao Zhang, Fangtao Yan, Jian Shen, Abdullah A. Alarfaj, Abdurahman Hajinur Hirad
Vol. 59 · Issue 4 · pp. 1375–1384
Original Article
Evaluating Myricetin as a CDK2 Inhibitor in Lung Cancer: In silico and in vitro Assessment of a Flavonoid-Based Small Molecule
Abdulaziz Asiri
Vol. 59 · Issue 4 · pp. 1385–1394
Original Article
Pennogenin Exerts Anti-inflammatory and Anti-nociceptive Effects in Several Models of Inflammation and Nociception in Mice
Yan Tao, Nan Cai, Juxia Zhang, Yaoping Zhao, Yan Zhou, Pengfei Liu
Vol. 59 · Issue 4 · pp. 1395–1407
Original Article
Modulation of Tuberculosis Pathway by Phaseolus vulgaris: An in silico Approach
Pradeep Kumar Mavinatop Ramanagouda, Santosh Basavaraj Patil, Sangameshwar Girimallappa Halkavatagi, Pankaj Kumar, Gupta Dheeraj Rajesh, Manisha Kuvalekar
Vol. 59 · Issue 4 · pp. 1408–1418
Original Article
Ameliorative Wound Healing Potency of Koenimbine via Attenuation of Inflammatory Cytokines in Hyperglycemia-Induced Rodent Model
Jing Xu, Fei Wang, Minjuan Zhang, Maoyuan Chen, Ke Zhao, Yang Liu, Dong Li
Vol. 59 · Issue 4 · pp. 1419–1428
Original Article
Harnessing Saussurea lappa for Anti-leishmanial, Anti-toxoplasmic, and Anti-bacterial Activity: Molecular and Computational Insights
Manal Mohamed Elhassan Taha, Siddig Ibrahim Abdelwahab, Muruganantham Bharathi, Waleed S. Koko, Ibrahim S. Al Nasr, Tariq A. Khan, Mohamed Eltaib Elmobark, Zia ur Rehman, Sivakumar S. Moni, Syam Mohan, Bassem Oraibi, Hassan Ahmad Alfaifi, Dina Abdulrahman Ismail Albadawi, Ahmed Ali Jerah, Yasir Babiker, Saleh M Abdullah, Ibrahim Abdel Aziz Ibrahim, Abdullah Farasani
Vol. 59 · Issue 4 · pp. 1429–1443
Original Article
Pharmacological Evaluation of Buchanania lanzan Bark Against Alcohol Induced Liver Cirrhosis in Rats
Namrata Soundatte, Namit Kudatarkar, Rajashekar Chavan
Vol. 59 · Issue 4 · pp. 1444–1455
Original Article
Liquiritin Ameliorates Streptozotocin-Induced Gestational Diabetes in Pregnant Rat Model by Inhibiting Inflammation and Oxidative Stress Responses
Jiejie Xing, Fang Wang, Junxiu Wei, Chenyuan Cao
Vol. 59 · Issue 4 · pp. 1456–1465
Original Article
Wogonoside Mitigates Inflammation and Cell Proliferation via Modulation of NF-κB Signalling Pathway in DMBA-Induced Mammary-Preclinical Model
Chenyang He, Yu Zhang, Yan Diao, Xingcong Ma, Guochao Mao, Xinyu Wei, Yang Zhao
Vol. 59 · Issue 4 · pp. 1466–1473
Original Article
Neutralizing Effects of Mimosa pigra Stem-Bark against Selected Snake Venom from Malaysian Habitat
Nor Safwan Nor Afendi, Noor Syahila Ahamad Saferi, Vishal Bhagwan Badgujar, Nur Fatin Afiqah Mohd Fazil, Farheen Sami, Sangita Badgujar, Hameeth Shah, Arun Kumar, Shahnaz Majeed, Mohammed Tahir Ansari
Vol. 59 · Issue 4 · pp. 1474–1482
Original Article
In vitro and in silico Analysis Protosappanin B Exerts Anti-Tumor Activity on Breast Cancer Cells via Activating Pro-Apoptotic Caspase Enzymes
Xia Zhang, Shuangnian Deng
Vol. 59 · Issue 4 · pp. 1483–1492
Original Article
Exploring Factors Affecting the Quantitative Analysis of Vitexin, Imperatorin and Gallic Acid in Tri-Kaysornmas Formulation
Suphatson Limsakul, Wissuta Roopngam, Yanisa Voeisarn, Thanaporn Pongmanachai, Yutthana Chotritthirong, Orawan Monthakantirat, Charinya Khamphukdee, Yaowared Chulikhit, Supawadee Daodee
Vol. 59 · Issue 4 · pp. 1493–1500
Original Article
Atorvastatin Ameliorates Neuroinflammatory Response in Experimental Intracerebral Hemorrhage Rats through the GSK-3β/β-Catenin Pathway
Jing Zhao, Mei Li, Lingling Zhang, Qi Zhang
Vol. 59 · Issue 4 · pp. 1501–1510
Original Article
Modulatory Effects of Dietary Saturated Versus Omega-3 Fatty Acids on Cognitive Impairment, Depressive-Like Behavior, HPA Axis Dysregulation and Systemic Inflammation in Monosodium Glutamate-Treated Young Male Rats
Hebatallah Husseini Atteia, Amal F. Gharib, Mervat El-Sayed Askar, Manar Hamed Arafa, Gehan A. Ahmed, Amr Tawfik Sakr
Vol. 59 · Issue 4 · pp. 1511–1521
Original Article
In silico and in vivo Evaluation of Antitumor Drugs against P. falciparum 3D7 Inhibit the Parasite Growth
Mohammad Aatif, Mohd Farhan, Ghazala Muteeb
Vol. 59 · Issue 4 · pp. 1522–1533
Original Article
Silencing of S100A16 in Cervical Cancer Cells Inhibits Cancer Cell Growth by Inducing Autophagy via PI3K/AKT/ mTOR Signaling Pathway
Haibin Zhang, Wenhu Xing, Yufeng Li, Xianyun Xu
Vol. 59 · Issue 4 · pp. 1534–1545
Original Article
Afzelin Prevents against Lipopolysaccharide-Induced Acute Lung Injury and Sepsis via Inhibiting the Inflammatory Mediators
Honghui Zhao
Vol. 59 · Issue 4 · pp. 1546–1552
Original Article
Herniarin Mitigates High-Fat Diet-Induced Atherosclerosis in Rats via Regulation of Hyperlipidemia, Endothelial Dysfunction, Inflammation and Oxidative Stress
Jingyue Lai, Zongyu Li, Ying Zhang, Hao Guan, Jiancang Ma
Vol. 59 · Issue 4 · pp. 1553–1564
Original Article
Therapeutic Potential of Lacidipine against 3- Nitropropionic Acid Induced Huntington's Disease: Based on Molecular Docking, Anti-Inflammatory and Neuroprotective Effects
Samiyah Alshehri, Muhammad Afzal, Sana Saeed Alqarni, Sattam Khulaif Alenezi, Khalid Saad Alharbi, Mohammad Jaffar Sadiq Mantargi, Imran Kazmi, Nadeem Sayyed, Faisal Imam
Vol. 59 · Issue 4 · pp. 1565–1581
Original Article
In silico and In vitro Characterization of Potent CDK2 Inhibitors as Probable Cancer Therapeutics
Akram Ahmed Aloqbi
Vol. 59 · Issue 4 · pp. 1582–1602
Original Article
Strengthening Finerenone Assessment: A Central Composite Design Viewpoint for Liquid Chromatographic Method Development
Paul Richard, Sarath Vothani, Srikrishna Theerthala, Kishore Boddu, Vasanth PM
Vol. 59 · Issue 4 · pp. 1603–1612
Original Article
Analytical Method Development and Validation by RP-HPLC and UV Spectrophotometric for Estimation of Daprodustat in Bulk and Pharmaceutical Dosage Form
Pranita Prabhakar Patil, Sunita Sunil Gagare, Ashish Suresh Jain
Vol. 59 · Issue 4 · pp. 1613–1622
Original Article
Identification and Comparison of Phytoconstituents of Essential Oil and Methanolic Extracts of Leaves and Rhizomes of Elettariopsis curtisii Grown in Malaysia via GCMS Analysis
Engku Nurul Najlaa, Sadia Sultan, Kamran Ashraf
Vol. 59 · Issue 4 · pp. 1623–1632
Original Article
Impact of Pharmacist-Led Training on Breast Cancer Awareness and Knowledge: A Quasi-Experimental Pre-Post Study
Zekiye Yılmaz, Ceren Eliçetin
Vol. 59 · Issue 4 · pp. 1633–1644