Medicinal Plants and Herbal Formulations Ameliorating Neurodegeneration: Remedies Combating Parkinson’s and Alzheimer’s Disease

Neuronal degeneration, characterized by progressive and irreversible loss of structure and function of neurons, could be a physiological age related or pathological intervention resulting in death of neuronal tissues. Neurodegenerative disease (ND) like Parkinson’s Disease (PD) and Alziemer’s Diseases (AD) aving molecular complexity in pathogenesis resulting in prominent loss of normal physiology of an individual. Practically, ND are incurable but by therapeutic approaches the loss of neurons and progress of disease is controlled but these drugs are associated with many unwanted effects. Herbals have been used from ancient times and referred to as conventional treatment methods to treat neurodegenerative disease having natural healing power and less side effects. Phytochemicals like Alkaloids, terpenes, saponins, phenols, flavonoids, etc. have major mechanisms behind management of most of the ND. In this review we briefly discussed some medicinal plants which have neuroprotective activities against ND specially AD and PD along with its mechanism of actions behind their pharmacological activities. Some herbal formulations used as traditional medicines to treat neurodegenerative disease worldwide are also briefly discussed.