Phytochemical and Pharmacological Screening of Begonia grandis Dryand

Pendy, Srinivasarao; Nallamothu, Krishna; Seru, Ganapaty; Katta, Sunitha; Mondal, Sumanta

doi:10.4103/pr.pr_67_20

Original ArticlePharmacognosy ResearchVol. 12 | Issue 4 | pp. 375–379Open access

Phytochemical and Pharmacological Screening of Begonia grandis Dryand

¹,
¹,
²^*,
²,
²

¹ Research and Development Wing, Divis Laboratories Ltd, Visakhapatnam, Andhra Pradesh, INDIA.
² GITAM Institute of Pharmacy, GITAM (Deemed to be University), Visakhapatnam, Andhra Pradesh, INDIA.

Correspondence: Ganapaty Seru
GITAM Institute of Pharmacy, GITAM (Deemed to be University), Visakhapatnam, Andhra Pradesh, INDIA.
Email: ganapatyseru@gmail.com

Received:: Jul 8, 2020
Accepted:: Sep 15, 2020
DOI:: 10.4103/pr.pr_67_20

How to cite

Pendy, S., Nallamothu, K., Seru, G., Katta, S., & Mondal, S. Phytochemical and Pharmacological Screening of Begonia grandis Dryand. Pharmacognosy Research, 12(4), 375–379. https://doi.org/10.4103/pr.pr_67_20

Abstract

Begonia grandis Dryand (Family: Begoniaceae) was screened for its phytoconstituents and evaluated for its ethnomedicinal potential as an antioxidant and hepatoprotective agent. The preliminary phytochemical studies of the B. grandis revealed the presence of alkaloids, flavonoids, glycosides, triterpenoids, and steroids. Antioxidant effect of the methanolic extract was assessed by DPPH, superoxide, hydroxyl radical scavenging activity, and hepatoprotective effect by CCl4-induced hepatotoxicity. The extract showed significant antioxidant and hepatoprotective effects at a dose of 400 mg/kg similar to that observed in ascorbic acid and silymarin.

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Article metadata

Title	Phytochemical and Pharmacological Screening of Begonia grandis Dryand
Authors	Srinivasarao Pendy; Krishna Nallamothu; Ganapaty Seru; Sunitha Katta; Sumanta Mondal
Affiliations	Research and Development Wing, Divis Laboratories Ltd, Visakhapatnam, Andhra Pradesh, INDIA.; GITAM Institute of Pharmacy, GITAM (Deemed to be University), Visakhapatnam, Andhra Pradesh, INDIA.
Corresponding author	ganapatyseru@gmail.com
Journal	Pharmacognosy Research
Volume / Issue	Vol. 12, Issue 4

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