Review ArticlePharmacognosy ReviewsVol. 20 | Issue 39 | pp. 54–62Open access
Targeting Tumor Growth and Progression in Carcinoma Prevention through Natural Catechol as Chemo Preventive Agents
- 1,
- 2*,
- 3
- 1 Department of Pharmacology, Narayan Institute of Pharmacy, Gopal Narayan Singh University, Sasaram, Bihar, INDIA.
- 2 Department of Pharmacognosy, SRM Modinagar College of Pharmacy, Faculty of Medicine and Health Sciences, SRM Institute of Science and Technology, Delhi NCR campus, Ghaziabad, Uttar Pradesh, INDIA.
- 3 Department of Pharmaceutical Analysis, Narayan Institute of Pharmacy, Gopal Narayan Singh University, Sasaram, Bihar, INDIA.
Published in Pharmacognosy Reviews
Correspondence: Sandip Chatterjee
Department of Pharmacognosy, SRM Modinagar College of Pharmacy, Faculty of Medicine and Health Sciences, SRM Institute of Science and Technology, Delhi NCR campus, Ghaziabad, Uttar Pradesh, INDIA.
Email: sandipkarna1994@gmail.com
- Received:
- Dec 3, 2025
- Accepted:
- Feb 24, 2026
- DOI:
- 10.5530/phrev.20260028
How to cite
Krishna, S., Chatterjee, S., & Goswami, P. K. Targeting Tumor Growth and Progression in Carcinoma Prevention through Natural Catechol as Chemo Preventive Agents. Pharmacognosy Reviews, 20(39), 54–62. https://doi.org/10.5530/phrev.20260028
Abstract
Green tea is rich in catechins, which are polyphenolic chemicals that have strong anticancer effects through pro-apoptotic, anti-inflammatory, and antioxidant processes. They alter a number of molecular pathways, including as those that control the course of the cell cycle, limit angiogenesis, and reduce metastasis. With traditional Chemotherapeutics, Epigallocatechin Gallate (EGCG), the most researched catechin, exhibits synergistic actions that increase efficacy and decrease toxicity. Catechins may serve as both preventive and therapeutic agents in the treatment of carcinoma, according to data from in vitro, in vivo, and a small number of clinical investigations. However, issues like poor absorption and varying patient reactions call for sophisticated administration methods and extensive clinical testing.
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Article metadata
| Title | Targeting Tumor Growth and Progression in Carcinoma Prevention through Natural Catechol as Chemo Preventive Agents |
|---|---|
| Authors | Siddhant Krishna; Sandip Chatterjee; Pawan Kumar Goswami |
| Affiliations | Department of Pharmacology, Narayan Institute of Pharmacy, Gopal Narayan Singh University, Sasaram, Bihar, INDIA.; Department of Pharmacognosy, SRM Modinagar College of Pharmacy, Faculty of Medicine and Health Sciences, SRM Institute of Science and Technology, Delhi NCR campus, Ghaziabad, Uttar Pradesh, INDIA.; Department of Pharmaceutical Analysis, Narayan Institute of Pharmacy, Gopal Narayan Singh University, Sasaram, Bihar, INDIA. |
| Corresponding author | sandipkarna1994@gmail.com |
| Journal | Pharmacognosy Reviews |
| Volume / Issue | Vol. 20, Issue 39 |
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