Therapeutic Potential of Vitex negundo: A Comprehensive Review of Its Medicinal Properties

Vitex negundo L., commonly known as Nochi in Tamil, is a widely distributed medicinal plant valued in traditional medicine for its diverse therapeutic properties. It contains a rich array of secondary metabolites, including flavonoids, alkaloids, tannins, and phenolic compounds, which contribute to its broad pharmacological potential. This review aims to provide a comprehensive overview of the general medicinal significance of based on existing scientific and ethnobotanical evidence. To summarize its phytochemical composition, highlight its general pharmacological activities, and discuss its role in traditional medicine, along with current research trends and conservation concerns. The available literature on the plant’s bioactive constituents, extraction methods, and reported biological activities highlights its potential as a source of natural products. V. negundo represents a valuable medicinal resource with promising applications in natural product research and drug development. Further studies on its bioactive compounds, standardization, and sustainable extraction are necessary to explore and harness its therapeutic potential fully. This review highlights the multifaceted role of V. negundo in disease prevention and treatment, emphasizing the need for further pharmacological and clinical investigations to establish its efficacy and safety for modern therapeutic use