Volume 60, Issue 2

Review Article

Bioequivalence and Bioavailability Studies: Regulatory Assessment and Study Design Considerations and Pharmacokinetic Parameters

Atharva Surendra Bhalerao, Sandeep Sonawane

Vol. 60 · Issue 2 · pp. 460–466

https://doi.org/10.5530/ijper.20260065

Review Article

Overcoming Implementation Challenges: A Comprehensive Review of ASEAN Medical Device Directive (AMDD) Regulatory Harmonization

Karthikeyan Vetrivel, Murugappan Mahalingam, Vivekanandan Elango, Yusuf Mansor, Kshitija Dilip Nikam

Vol. 60 · Issue 2 · pp. 467–473

https://doi.org/10.5530/ijper.20260969

Review Article

Advancing Pharmaceutical Reliability: Innovations in Stability-Indicating Assay Methods

Daram Sushma Reddy, Gurupadayya Bannimath, Sruthi Kondru, Anupama Manepally, Manognya Kaveti, Rupshee Jain

Vol. 60 · Issue 2 · pp. 474–484

https://doi.org/10.5530/ijper.20261191

Original Article

Multidisciplinary Approach for Designing of Drug Delivery System: Leveraging Artificial Intelligence and Experimental Design for Enhanced Helicobacter pylori Formulation Optimization

Manivasakam Prakash, Venkateswaramurthy Nallasamy, Senthil Venkatachalam, Anandharaj Govindaraj

Vol. 60 · Issue 2 · pp. 485–493

https://doi.org/10.5530/ijper.20261624

Review Article

Animal Models and Pathogenesis on Neurodegenerative Disorders (Huntington’s Disease): An Updated Review

Diksha Diwakar, Shahbaz Khan, Shivani lodha, Deepika Pal, Dinesh Kumar, Devesh Kumar, Alka Lohani

Vol. 60 · Issue 2 · pp. 494–510

https://doi.org/10.5530/ijper.20262132

Original Article

Innovative Exploration of the Connotation and Education and Training Practice Path of Outstanding Pharmaceutical Engineers

Juan Chen, Yingying Ji, Hongliang Qian, Jiayu Li, Chunmeng Sun, Xinran Wang, Cheng Jiang

Vol. 60 · Issue 2 · pp. 511–520

https://doi.org/10.5530/ijper.20266248

Original Article

Design Expert Optimization of Transdermal Patches for Effective Prolonged Release of Alzheimer's Medications

Bariki Rajasekhar, Haranath Chinthaginjala

Vol. 60 · Issue 2 · pp. 521–531

https://doi.org/10.5530/ijper.20260354

Original Article

Formulation and Evaluation of Cilnidipine Loaded Nanoparticles for Enhanced Solubility

Mahalingan Kuppan, Vedamurthy Joshi, Muhammad Shahzad Chohan, Nagaraja Sreeharsha

Vol. 60 · Issue 2 · pp. 532–538

https://doi.org/10.5530/ijper.20263140

Original Article

Formulation Development and Evaluation of Fast Dissolving Sublingual Film of Apixaban: Design of Experiment-Based Approach

Abhishek Kanugo, Mohammad Adnan

Vol. 60 · Issue 2 · pp. 539–549

https://doi.org/10.5530/ijper.20265848

Original Article

Formulation Development and Evaluation of Fast Dissolving Tablets of Bisoprolol Fumarate using Response Surface Technique

Ramana Gangireddy, Shaik Aminabee, Kunderu Ravi Shankar, Raghavendra Kumar Gunda, Hari Krishna Gantasala, Akarsh Chowdary Kakarala, Kanamarlapudi Lakshmi Chandana, Chetan Mokkapati

Vol. 60 · Issue 2 · pp. 550–557

https://doi.org/10.5530/ijper.20266837

Original Article

Mitigating Cisplatin-Induced Nephrotoxicity with Morin: A Flavonoid's Role in Nrf2/HO-1 Pathway Activation in HEK 293 Cells

Jianliang Qu, Wei Song, Abdullah A. Alarfaj, Abdurahman Hajinur Hirad

Vol. 60 · Issue 2 · pp. 558–565

https://doi.org/10.5530/ijper.20261971

Original Article

Effect of Ciprofloxacin on Some Oxidative Stress Parameters and TNF-α, IL-6 and BDNF in Diabetic Rats with Urinary Tract İnfection Induced by Escherichia coli

Nur Akman, Ahmet Ufuk Komuroglu

Vol. 60 · Issue 2 · pp. 566–574

https://doi.org/10.5530/ijper.20266403

Original Article

Exploring a Novel Approach: In vitro Cytotoxicity Study of Capecitabine Loaded Resealed Erythrocytes

Anuradha Niranjan Chivate, Niranjan Dattatray Chivate, Sudhir Sunil Patil, Shivsharan Basavraj Dhadde

Vol. 60 · Issue 2 · pp. 575–581

https://doi.org/10.5530/ijper.20266766

Original Article

Unraveling the Therapeutic Potential of Apigenin: Targeting CDK6 in Cancer Treatment

Hani Alothaid

Vol. 60 · Issue 2 · pp. 582–597

https://doi.org/10.5530/ijper.20260852

Original Article

Protective Mechanism of NLRP3 Inflammatory Bodies Mediated by Dexmedetomidine on Renal Injury in Rats with Hemorrhagic Shock

Yanlin Zhou, Yumei Shuai, Min Yang

Vol. 60 · Issue 2 · pp. 598–603

https://doi.org/10.5530/ijper.20260639

Original Article

Differential Evaluation of Multi-Index Components in Different Parts of Ophiopogon japonicus

Jiuhua Song, Qin Liu, Kai Shi

Vol. 60 · Issue 2 · pp. 604–613

https://doi.org/10.5530/ijper.20260713

Original Article

Topiramate Versus Acetazolamide for Idiopathic Intracranial Hypertension. A Real-World Data-Based Multicenter Retrospective Study

Mahmoud Mohamed Morsy, Ahmed Yasser Azzam, Muhammed Amir Essibayi, Alsaleem Mohammed Abadi, Nasser Abdulmohsen Alsabaani, Safar Abadi Alsaleem, Waleed Abdulwahab Aldhabaan, Hana Jihad Abukhadijah, Mohamed Darwesh Morsy, Aayushi Aarav Garg, David Joseph Altschu

Vol. 60 · Issue 2 · pp. 614–629

https://doi.org/10.5530/ijper.20261194

Original Article

Schaftoside Attenuates Myocardial Ischemia/Reperfusion Injury in Streptozotocin-Induced Diabetic Rats

Ziye Wen, Tingting Zhang, Na Wang, Zeng Fan, Huihui Zhu, Zengxin Li

Vol. 60 · Issue 2 · pp. 630–641

https://doi.org/10.5530/ijper.20261984

Original Article

Green Synthesized Zinc Oxide Nanoparticles Using Musa acuminata Corm Extract and Its Anti-Cancer Activity

Hassani Rym

Vol. 60 · Issue 2 · pp. 642–651

https://doi.org/10.5530/ijper.20262292

Original Article

Berbamine Ameliorates LPS-Induced Inflammation in RAW264.7 Cells and Ovalbumin-Induced Allergic Asthma in Mice

Jianlin Zhao, Miaomiao Fu, Yan Sun

Vol. 60 · Issue 2 · pp. 652–662

https://doi.org/10.5530/ijper.20262086

Original Article

Hederagenin Shows Protective Effects Against Sodium Selenite-Induced Oxidative Stress and Cataractogenesis in Rats via Activation of Nrf2/HO-1 Pathway

Min Yang, Li Meng, Zhanrong Zhang, Wenjun Chen, Yanlong Li

Vol. 60 · Issue 2 · pp. 663–672

https://doi.org/10.5530/ijper.20262754

Original Article

Conessine as A Novel Anti-Quorum Sensing Agent against Streptococcus mutans: An in vitro Analysis of Biofilm Inhibition

Khloud H Alsaadi

Vol. 60 · Issue 2 · pp. 673–682

https://doi.org/10.5530/ijper.20262947

Original Article

Herb-Drug Interaction Evaluation on Concomitant Administration of IME-9 and Gliclazide in Preclinical Diabetic Rats

Archana Kondibhau Thikekar, Asha Byju Thomas, Sohan Satyanarayan Chitlange, Avinash Purushottam Sanap, Ramesh Ramchandran Bhonde, Somdatta Yashwant Chaudhari

Vol. 60 · Issue 2 · pp. 683–698

https://doi.org/10.5530/ijper.20267022

Original Article

Dose-Dependent Effects of Herbal Extract on Reproductive Health: Implications for Ovarian Structure, Organ Weight and Hormonal Balance in Female Rats

Aiman Ammari, Ahmad Alhimaidi, Ramzi Amran, Hossam Aljawdah, Mutee Murshed, Ahmad Rady

Vol. 60 · Issue 2 · pp. 699–706

https://doi.org/10.5530/ijper.20260951

Original Article

Cognitive-Enhancing and the Neuroprotective Propensity of Heartwood Caesalpinia sappan against D-Galactose- Induced Cognitive Impairments on Wistar Rats

Pooja Rangenahalli Chidananda Murthy, Bharathi Doddla Raghunathanaidu

Vol. 60 · Issue 2 · pp. 707–716

https://doi.org/10.5530/ijper.20260515

Original Article

Formulation and Evaluation of P-Naphthoquinone Casein Nanodispersions and their Antibacterial and Anticancer Activities

Anitha Manikandan Duraikannu, Shanmugaprakash Muthusamy, Thangavel Pichaiapaa Rajesh

Vol. 60 · Issue 2 · pp. 717–728

https://doi.org/10.5530/ijper.20261335

Original Article

Sophoricoside Alleviates Oxidative Stress and Inflammation in Streptozotocin-Induced Diabetes Mellitus in Rats

Jie Yang, Lu Yan, Xinrong Zhang, Jiawei Zhang

Vol. 60 · Issue 2 · pp. 729–738

https://doi.org/10.5530/ijper.20262129

Original Article

Formulation, Characterization, in vitro and MTT Cytotoxicity Evaluation of Pioglitazone HCl Films for Topical Administration

Karishma Singh, Archana Mehrotra, Sobhna Singh

Vol. 60 · Issue 2 · pp. 739–748

https://doi.org/10.5530/ijper.20262124

Original Article

Polydatin Induces Apoptosis in Thyroid Cancer TPC-I Cells by Regulating Apoptotic Proteins and Downregulating JAK/ STAT Pathway

Xiao Zhao, Kai Gai, Bin Lin

Vol. 60 · Issue 2 · pp. 749–757

https://doi.org/10.5530/ijper.20262136

Original Article

Cardioprotective Effects of Piperlongumine against Doxorubicin-Induced Myocardial Infarction via Down-Regulating Cardiac Biomarkers in Rats

Guo Xiong

Vol. 60 · Issue 2 · pp. 758–767

https://doi.org/10.5530/ijper.20262259

Original Article

Formulation, Characterization, and Evaluation of Naringin-Loaded Phytosomal Gel and it’s in vivo Anti-Inflammatory Activity by Carrageenan Animal Model

Satish Kavatagimath, Aqeeb Mevegar, Nayeem Khatib

Vol. 60 · Issue 2 · pp. 768–779

https://doi.org/10.5530/ijper.20263075

Original Article

Combinatory Effects of Resveratrol and Curcumin in a Murine Model of Acuteon Chronic Liver Failure

Jing Zhang, Xiaohong Wang, Qingchun Li, Wenqian Mou, Ting Zhu, Huanhuan Ba, Hamed Mirzaee, Shujuan Yang

Vol. 60 · Issue 2 · pp. 780–789

https://doi.org/10.5530/ijper.20262571

Original Article

Peanut Skin Extract Attenuates Doxorubicin Induced Myocardial Infarction by Alleviating Cardiac Inflammation, Oxidative Stress and Histological Changes in Wistar Rats

Mohd Wasim, Aamir Khan, Ashif Iqubal, Syed Ehtaishamul Haque

Vol. 60 · Issue 2 · pp. 790–797

https://doi.org/10.5530/ijper.20267202

Original Article

Haifei Zhang, Kai Li

Vol. 60 · Issue 2 · pp. 798–808

https://doi.org/10.5530/ijper.20262622

Original Article

Recent Advances in Pharmacotherapeutic Approaches for Alopecia areata: A Systematic Review of Clinical Trials from the Last Decade

Ahmad Assiri

Vol. 60 · Issue 2 · pp. 809–829

https://doi.org/10.5530/ijper.20262806

Original Article

Wound Healing Potential of Curcumin and Colostrum- Loaded Liposomes in Diabetic Foot Ulcers

Isha Chawla, Ishrat Zahoor, Seema Bansal, Anroop B Nair, Sumeet Gupta

Vol. 60 · Issue 2 · pp. 830–844

https://doi.org/10.5530/ijper.20263371

Original Article

Antimicrobial Activity of Acacia tortilis (Talha of Tindouf) against Bacteria and Fungi Isolated from Various Water Sources in the Elbayadh Region (Algeria)

Moghtet Snoussi, Menad Najett, Benyagoub El Hassen, Hamed Djahira, Ait Saada Djamel

Vol. 60 · Issue 2 · pp. 845–851

https://doi.org/10.5530/ijper.20265564

Original Article

Development and Validation of UPLC-PDA and UV Methods for the Quantitative Estimation of Ascorbic Acid (ASAC) in Pharmaceutical Formulations

Wasim Ahmad, Nuzhat Banu, Ayaz Ahmad, Yousif Amin Hassan, Manal Surour, Rawan Rashad Aleid, Munfis Samir Patel, Sharell Lewis, Kamran Ashraf

Vol. 60 · Issue 2 · pp. 852–860

https://doi.org/10.5530/ijper.20261506

Original Article

Development and Validation of the Stability-Indicating RP-HPLC Method to Estimate Olaparib in Graphene Quantum Dot Nanoformulation Using Analytical Quality by Design (AQbD) Principles

Pooja Rayanade, Archana Patil, Yadishma Gaude, Abhijit Salokhe, Priya Shetti

Vol. 60 · Issue 2 · pp. 861–868

https://doi.org/10.5530/ijper.20261817

Original Article

Validated HPTLC Method for Accurate Measurement of Quercetin in Ficus benghalensis Linn. Bark Extract

Sangita Kumari, Mahendra Pratap Chopra

Vol. 60 · Issue 2 · pp. 869–875

https://doi.org/10.5530/ijper.20261891

Original Article

Coordination Scaffolds of Schiff Base Derived from Imatinib Amine: Synthesis, Spectroscopic and in vitro Biological Screening

Prashant Gajera, Milan Vadodaria, Rahul Parmar

Vol. 60 · Issue 2 · pp. 876–883

https://doi.org/10.5530/ijper.20260929

Original Article

Unveiling the Bioactive Potential of Mannich Bases: Synthesis, Characterization, and Biological Perspectives

Singirisetty Triveni, Yapuri Ashok Kumar, Vijaya Jyothi Mallela, Gangadhar Gari Ganesh Sai, Nukala Vedavathi, Vishwanadhapalli Raja Rajeshwari, Varikuti Janardhana, Chilamakuru Naresh Babu

Vol. 60 · Issue 2 · pp. 884–894

https://doi.org/10.5530/ijper.20261518

Original Article

Virtual Workshop on Antibiotic Use and Resistance for Malaysian Secondary School Students

Jasmine Shi Qi Leong, Sui Ling Janet Tan, Priya Madhavan, Sharina Hamzah, Nusaibah Abdul Rahim, Hui Yin Yow

Vol. 60 · Issue 2 · pp. 895–902

https://doi.org/10.5530/ijper.20261587

Original Article

Novel EDC-Crosslinked Hydroxypropyl banana (Musa paradisiaca) starch as a Superdisintegrant for Enhanced Oral Delivery of Pioglitazone Hydrochloride in Orodispersible Tablets

Samyuktha Metta, Srinivas Lankalapalli

Vol. 60 · Issue 2 · pp. 903–917

https://doi.org/10.5530/ijper.20261872

Original Article

TSH Suppression Induces Anxiety- and Depression-like Behaviors in Rats, With Hippocampal 5-HT Loss, Notch Activation, and a Neurogenesis-Apoptosis Imbalance

Yikun Zhao, Honglin Jiang, Huiyuan Shang, Zhongyuan Xia

Vol. 60 · Issue 2 · pp. 1256–1267

https://doi.org/10.5530/ijper.20264130