Volume 58

Volume 58, Issue 4

research-article
Efficacy and Safety of Erythromycin in the Treatment of Mycoplasma Pneumonia in Children: A Systematic Review and Meta-Analysis
Mingxiu Sun, Zhirui Xue, Jiarui Li, Likun Du
Vol. 58 · Issue 4 · pp. 1007–1014
https://doi.org/10.5530/ijper.58.4.113
research-article
From Risk to Resilience: Uncovering Drug Recall Trends and Bolstering Safety Strategies
Venkateswara Raju Kalidindi, Bandaru Mani Sai Durga, Lakshmi Prasanthi Nori
Vol. 58 · Issue 4 · pp. 1015–1033
https://doi.org/10.5530/ijper.58.4.114
research-article
Plant Bioactive Compounds: Crucial Pharmacological Properties and Role of Elicitors in Enhancing Production
Durga Anusha Sampath Kumar, Deepa Sankar Parasurama
Vol. 58 · Issue 4 · pp. 1034–1044
https://doi.org/10.5530/ijper.58.4.115
research-article
Standards of Child Resistant Packaging: A Regulatory View
Gowthami Kodlahalli Ravindra, Bhoopathi Subramaniam, Balamuralidhara Veeranna
Vol. 58 · Issue 4 · pp. 1045–1053
https://doi.org/10.5530/ijper.58.4.116
research-article
Research Progress in Mechanisms of Drug-Resistance of Macrolide Antibiotics Resistance in Mycoplasma pneumoniae
Meixuan Jia, Qingtao Li, Lijun Zhang, Xiaona Qian, Liyuan Tian, Zhihui Yan
Vol. 58 · Issue 4 · pp. 1054–1069
https://doi.org/10.5530/ijper.58.4.117
research-article
Rutaecarpine Induces Apoptosis via a Mitochondrial Membrane-Mediated Pathway in the Human Liver Cancer Cells (HepG2)
Xiaoyuan Zhuang, Yatian Wang, Shen Lin, Guoshan Zhang
Vol. 58 · Issue 4 · pp. 1070–1076
https://doi.org/10.5530/ijper.58.4.118
research-article
Leonurine Attenuates Streptozotocin-Induced Diabetic Nephropathy in Rats by Mitigating Dyslipidemia and Inflammation
Lin Li, Qian Wang, Yan Gao, Li Zhang
Vol. 58 · Issue 4 · pp. 1139–1147
https://doi.org/10.5530/ijper.58.4.125
research-article
Preclinical Studies of Euphorbia lactea Aerial Extract on Atherogenic-Diet-Induced Atherosclerosis
Zubair Khan, Nazia Siddiqui, Garima Agarwal, Anurag Chaudhary, Syed Salman Ali, Abdel-Nasser El-Shorbagi, Sachin Chaudhary, Prabhash Nath Tripathi
Vol. 58 · Issue 4 · pp. 1149–1156
https://doi.org/10.5530/ijper.58.4.126
research-article
Biological Activity of Ethanol Extract of Terminalia chebula Dried Carp against Bacterial Wilt of Lycopersicum esculentum and its Mechanism of Inhibition
Padmalatha Ajith, SB Prabha
Vol. 58 · Issue 4 · pp. 1157–1166
https://doi.org/IndJPhaEdRes-58-4-1157
research-article
Phytochemical Study, Polyphenols Determination and Evaluation of Antioxidant Activity of Satureja calamintha from Morocco
Asma Halmoune, Nadia Salhi, EL Finou Hamza, Ait Benlabchir Abdessamad, Khfif Khalid, Zaid Abdelhamid, El Rhaffari Ihoussaine
Vol. 58 · Issue 4 · pp. 1167–1173
https://doi.org/10.5530/ijper.58.4.128
research-article
The Therapeutic and Toxic Effects of Artemisia herba alba Extract on the Reproductive System and Fertility of Male Rabbits Oryctolagus cuniculus
Yasmina Moumen, Hichem Khammar, Cherif Abdennour, Yacine Zerouki, Meriem Zitouni
Vol. 58 · Issue 4 · pp. 1174–1183
https://doi.org/10.5530/ijper.58.4.129
research-article
Enhancement of Solubility and Dissolution Rate of Poorly Soluble Anticancer Drug Using Nanostructured Lipid Carrier Based Drug Delivery System
Vidya Sabale, Manasi Jiwankar, Prafulla Sabale
Vol. 58 · Issue 4 · pp. 1184–1188
https://doi.org/10.5530/ijper.58.4.130
research-article
Antibacterial Effects of Bioactive Boswellic Acids Loaded Chitosan Nanoparticles against Gram-Positive and Gram-Negative Bacteria
Neeta Rathi, Satyender Kumar, Seema, Harish Dureja
Vol. 58 · Issue 4 · pp. 1189–1197
https://doi.org/10.5530/ijper.58.4.131
research-article
Development and Characterization of Liquisolid Compact to Improve Dissolution of an Antihypertensive Drug
Arvinder Kaur, Sachin Verma, Deepa Bagur Paramesh, Nawaz Mahammad
Vol. 58 · Issue 4 · pp. 1198–1204
https://doi.org/10.5530/ijper.58.4.132
research-article
Design, Optimization, and in vitro Evaluation of Orally Disintegrating Tablets Containing Amlodipine Besylate
Sevinç Şahbaz, Setenay Özer-Önder, Timuçin Uğurlu
Vol. 58 · Issue 4 · pp. 1205–1214
https://doi.org/10.5530/ijper.58.4.133
research-article
Formulation of Pregabalin-Loaded Trimethyl Chitosan Microspheres for Nasal Drug Delivery: In vitro, ex vivo and in vivo Characterization
Sonwane Priyanka, Qutub Mohammad, Umekar Milind, Taksande Jayshree
Vol. 58 · Issue 4 · pp. 1215–1224
https://doi.org/10.5530/ijper.58.4.134
research-article
Synthesis, Anti-inflammatory and in silico Studies of few novel 1,2,4-Triazole Derived Schiff Base Compounds
Deepanshu Vishwakarma, Surya Prakash Gupta
Vol. 58 · Issue 4 · pp. 1235–1241
https://doi.org/10.5530/ijper.58.4.136
research-article
Coumarin-1,2,3-Triazole Hybrids as Promising Antibacterial Agents: In silico Molecular Docking, ADMET and Molecular Dynamics Simulation Studies (Exploring in silico Antibacterial Potential of Coumarin-1,2,3-triazoles)
Krishna Narayan Mishra, Mayank Rashmi, Harish Chandra Upadhyay
Vol. 58 · Issue 4 · pp. 1242–1254
https://doi.org/10.5530/ijper.58.4.137
research-article
A Simultaneous Quantification of Four Potential Genotoxic Impurities Purinediol Hydrochloride, N7-Isomer, Monoalkyl Contaminant and Diacetyl Purine Present in Penciclovir Using LC-MS/MS
Nagasurendra Reddy Varampati, Devanna Nayakanti
Vol. 58 · Issue 4 · pp. 1255–1266
https://doi.org/10.5530/ijper.58.4.138
research-article
Electrometric Study on Nature and Stability of Co^II, Ni^II and Cu^II Complexes with 5-Sulfosalicylic Acid in DMSO-Water Mixtures
Malla Balakrishna
Vol. 58 · Issue 4 · pp. 1267–1276
https://doi.org/10.5530/ijper.58.4.139
research-article
HR-LCMS Metabolite Profiling and in silico Evaluation of the Antidiabetic Activity of Methanolic Leaf Extract of Chrozophora rottleri (Geiseler) A. Juss. Ex Spreng.
Srilakshmi Nallapaty, Narender Malothu, Sathish Kumar Konidala, Anka Rao Areti, Chakravarthi Guntupalli
Vol. 58 · Issue 4 · pp. 1277–1286
https://doi.org/10.5530/ijper.58.4.140
research-article
GCMS and LCMS/MS Based Analysis for the Identification and Characterization of Bioactive Metabolites of Seaweed Kappaphycus striatus as an Anti-hypertensive and Anti-hypercholesterolemic Agent
Hannis Fadzillah Mohsin, Zolkapli Eshak, Sadia Sultan, Wasim Ahmad, Mohammad Humayoon Amini, Kamran Ashraf
Vol. 58 · Issue 4 · pp. 1287–1298
https://doi.org/10.5530/ijper.58.4.141
research-article
Development and Validation of a New RP-HPLC Method for the Simultaneous Estimation of Nirmatrelvir, Ritonavir and Molnupiravir in Formulated Nanosponges, Plasma Samples and its Pharmacokinetic Study
Vyshali Veerareddy, Kumaraswamy Gandla
Vol. 58 · Issue 4 · pp. 1299–1310
https://doi.org/10.5530/ijper.58.4.142
research-article
A Cross-Sectional Study of Community Attitude towards Herbal Products against Hepatobiliary Diseases in Northern Cyprus
Umut Sõzüõz, Azmi Hanoğlu, Fehmi Burak Alkaş, Duygu Yiğit Hanoğlu, Ali Hikmet Meriçli, Dudu Őzkum Yavuz
Vol. 58 · Issue 4 · pp. 1311–1317
https://doi.org/10.5530/ijper.58.4.112
research-article
Evaluation of the Knowledge, Opinion, and Approaches of Pharmacists, Physicians, Dieticians, and the Public on Herbal Products Used for Weight Control and Slimming in Northern Cyprus
Bariş Şendal lzzet, Hasan Ulaş Yavuz, Dudu Özkum Yavuz
Vol. 58 · Issue 4 · pp. 1318–1327
https://doi.org/10.5530/ijper.58.4.111
research-article
A Prospective Observational Study on Assessment of Risk Factors, Complications and Clinical Efficacy of Hepatoprotectives and Antimicrobials in Treatment of Liver Diseases at Tertiary Care Teaching Hospital in Telangana
Jaya Sollu, Mounika Pulusu, Deepthi Peddaramamolla, Jharna Islam, Nikhil Soma, Chinnaeswaraiah Maram
Vol. 58 · Issue 4 · pp. 1328–1335
https://doi.org/10.5530/ijper.58.4.143
research-article
Augmented Optical Retention and Improved Antibacterial Activity against Conjunctivitis of Moxifloxacin Hydrochloride Entrapped in Microsponges in situ Gel: Formulation Evaluation and in vivo Remedial Value in Rabbits
Sangeet Kumar Sharma, Ishab Kumar, Ankur Rohilla, Ramchander Khatri, Tanuj Hooda, Seema Rohilla
Vol. 58 · Issue 4 · pp. 1336–1347
https://doi.org/u10.5530/ijper.58.4.144
research-article
Silencing PDCD4 Mediates TFEB Overexpression Promoting Proliferation, Migration and Invasion of Cervical Cancer HeLa Cells
Xing Gao, Ziying Liang, Yanan Yuan, Wenbo Liu
Vol. 58 · Issue 4 · pp. 1348–1355
https://doi.org/10.5530/ijper.58.4.145
research-article
Strategic Targeting of Plasmodium Dihydroorotate Dehydrogenase through Antimicrobial Artemisinin Chiral Centers and their Derivatives: An Integrative Study Using Network Pharmacology and Isothermal Titration Calorimetry
Zia ur Rehman
Vol. 58 · Issue 4 · pp. 1356–1372
https://doi.org/10.5530/ijper.58.4.146
research-article
The Effect of Sophoridine on NSCLC by Down Regulation of mTOR and NOTCH1
Mohammad Raghibul Hasan, Ali Hazazi, Ahad Amer Alsaiari, Fawaz M. Almufarriji, Amirah Albaqami, Osama Abdulaziz, Marwa K Darwish, Atul Kumar, Kapil Dev, Mohammed Ageeli Hakami
Vol. 58 · Issue 4 · pp. 1373–1379
https://doi.org/10.5530/ijper.58.4.147

Volume 58, Issue 4

Efficacy and Safety of Erythromycin in the Treatment of Mycoplasma Pneumonia in Children: A Systematic Review and Meta-Analysis

From Risk to Resilience: Uncovering Drug Recall Trends and Bolstering Safety Strategies

Plant Bioactive Compounds: Crucial Pharmacological Properties and Role of Elicitors in Enhancing Production

Standards of Child Resistant Packaging: A Regulatory View

Research Progress in Mechanisms of Drug-Resistance of Macrolide Antibiotics Resistance in Mycoplasma pneumoniae

Rutaecarpine Induces Apoptosis via a Mitochondrial Membrane-Mediated Pathway in the Human Liver Cancer Cells (HepG2)

Leonurine Attenuates Streptozotocin-Induced Diabetic Nephropathy in Rats by Mitigating Dyslipidemia and Inflammation

Preclinical Studies of Euphorbia lactea Aerial Extract on Atherogenic-Diet-Induced Atherosclerosis

Biological Activity of Ethanol Extract of Terminalia chebula Dried Carp against Bacterial Wilt of Lycopersicum esculentum and its Mechanism of Inhibition

Phytochemical Study, Polyphenols Determination and Evaluation of Antioxidant Activity of Satureja calamintha from Morocco

The Therapeutic and Toxic Effects of Artemisia herba alba Extract on the Reproductive System and Fertility of Male Rabbits Oryctolagus cuniculus

Enhancement of Solubility and Dissolution Rate of Poorly Soluble Anticancer Drug Using Nanostructured Lipid Carrier Based Drug Delivery System

Antibacterial Effects of Bioactive Boswellic Acids Loaded Chitosan Nanoparticles against Gram-Positive and Gram-Negative Bacteria

Development and Characterization of Liquisolid Compact to Improve Dissolution of an Antihypertensive Drug

Design, Optimization, and in vitro Evaluation of Orally Disintegrating Tablets Containing Amlodipine Besylate

Formulation of Pregabalin-Loaded Trimethyl Chitosan Microspheres for Nasal Drug Delivery: In vitro, ex vivo and in vivo Characterization

Synthesis, Anti-inflammatory and in silico Studies of few novel 1,2,4-Triazole Derived Schiff Base Compounds

Coumarin-1,2,3-Triazole Hybrids as Promising Antibacterial Agents: In silico Molecular Docking, ADMET and Molecular Dynamics Simulation Studies (Exploring in silico Antibacterial Potential of Coumarin-1,2,3-triazoles)

A Simultaneous Quantification of Four Potential Genotoxic Impurities Purinediol Hydrochloride, N7-Isomer, Monoalkyl Contaminant and Diacetyl Purine Present in Penciclovir Using LC-MS/MS

Electrometric Study on Nature and Stability of Co^II, Ni^II and Cu^II Complexes with 5-Sulfosalicylic Acid in DMSO-Water Mixtures

HR-LCMS Metabolite Profiling and in silico Evaluation of the Antidiabetic Activity of Methanolic Leaf Extract of Chrozophora rottleri (Geiseler) A. Juss. Ex Spreng.

GCMS and LCMS/MS Based Analysis for the Identification and Characterization of Bioactive Metabolites of Seaweed Kappaphycus striatus as an Anti-hypertensive and Anti-hypercholesterolemic Agent

Development and Validation of a New RP-HPLC Method for the Simultaneous Estimation of Nirmatrelvir, Ritonavir and Molnupiravir in Formulated Nanosponges, Plasma Samples and its Pharmacokinetic Study

A Cross-Sectional Study of Community Attitude towards Herbal Products against Hepatobiliary Diseases in Northern Cyprus

Evaluation of the Knowledge, Opinion, and Approaches of Pharmacists, Physicians, Dieticians, and the Public on Herbal Products Used for Weight Control and Slimming in Northern Cyprus

A Prospective Observational Study on Assessment of Risk Factors, Complications and Clinical Efficacy of Hepatoprotectives and Antimicrobials in Treatment of Liver Diseases at Tertiary Care Teaching Hospital in Telangana

Augmented Optical Retention and Improved Antibacterial Activity against Conjunctivitis of Moxifloxacin Hydrochloride Entrapped in Microsponges in situ Gel: Formulation Evaluation and in vivo Remedial Value in Rabbits

Silencing PDCD4 Mediates TFEB Overexpression Promoting Proliferation, Migration and Invasion of Cervical Cancer HeLa Cells

Strategic Targeting of Plasmodium Dihydroorotate Dehydrogenase through Antimicrobial Artemisinin Chiral Centers and their Derivatives: An Integrative Study Using Network Pharmacology and Isothermal Titration Calorimetry

The Effect of Sophoridine on NSCLC by Down Regulation of mTOR and NOTCH1