Review ArticleInternational Journal of Pharmaceutical InvestigationVol. 15 | Issue 3 | 2025 | pp. 703–724Open access
Exploring the Potential of Gastro Retentive Drug Delivery Systems: An Insightful Perspective
- 1,
- 1,
- 2,
- 3,
- 4,
- 1*
- 1 PSIT-Pranveer Singh Institute of Technology (Pharmacy), Kalpi Road, Bhauti, Kanpur, Uttar Pradesh, India.
- 2 Department of Pharmacognosy Amrutvahini College of Pharmacy Sangamner Dist- Ahmednagar, Maharashtra.
- 3 Department of Electronics and Communication Engineering, Greater Kolkata College of Engineering and Management, India- 743387.
- 4 Department of Formulation Research and Development, University of Iowa Pharmaceuticals, College of Pharmacy, University of Iowa, Iowa City, IA, USA.
Published in International Journal of Pharmaceutical Investigation
Correspondence: Ruchi Tiwari
PSIT-Pranveer Singh Institute of Technology (Pharmacy), Kalpi Road, Bhauti, Kanpur, Uttar Pradesh, India.
Email: tiwaridrruchi@gmail.com
Copyright: © 2025 Manuscript Technomedia. This is an open access article.
- Published:
- Jan 1, 2025
- Received:
- Nov 28, 2024
- Accepted:
- Mar 7, 2025
- DOI:
- 10.5530/ijpi.20250244
How to cite
Mishra, S., Shukla, P., Chumbhale, D. S., Dutta, P., Vellingiri, D., & Tiwari, R. (2025). Exploring the Potential of Gastro Retentive Drug Delivery Systems: An Insightful Perspective. International Journal of Pharmaceutical Investigation, 15(3), 703–724. https://doi.org/10.5530/ijpi.20250244
Abstract
In today’s modern world, there is a rapid increase in the control and systemic administration of drugs through the oral route, because of its various advantages like high patient compliance, easy dose administration and availability of various formulations. One of the novel approaches in this area is Gastro Retentive Drug Delivery Systems (GRDDs) is a systemic approach to increase the gastric residence time of the drug which results in the site-specific drug release of drug in the upper part of GIT for local and systemic effect of the drug. It is a unique approach that has become more popular in the last three decades. The sole purpose of this article is to summarize and present recent as well as past article which focuses on the GRDDs and their various aspects. This article addresses briefly on various aspects of GRDDs their classification, advantages and limitations, factors affecting gastric residence time, evaluation, recent advancements, regulatory requirements and future prospective of GRDDs.
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Article metadata
| Title | Exploring the Potential of Gastro Retentive Drug Delivery Systems: An Insightful Perspective |
|---|---|
| Authors | Saket Mishra; Priyanka Shukla; Deshraj Shyamkant Chumbhale; Pijush Dutta; Dhakshnamoorthy Vellingiri; Ruchi Tiwari |
| Affiliations | PSIT-Pranveer Singh Institute of Technology (Pharmacy), Kalpi Road, Bhauti, Kanpur, Uttar Pradesh, India.; Department of Pharmacognosy Amrutvahini College of Pharmacy Sangamner Dist- Ahmednagar, Maharashtra.; Department of Electronics and Communication Engineering, Greater Kolkata College of Engineering and Management, India- 743387.; Department of Formulation Research and Development, University of Iowa Pharmaceuticals, College of Pharmacy, University of Iowa, Iowa City, IA, USA. |
| Corresponding author | tiwaridrruchi@gmail.com |
| Journal | International Journal of Pharmaceutical Investigation |
| Volume / Issue | Vol. 15, Issue 3 (2025) |
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