Development of Resveratrol-Quercetin Face Serum: A Dual Defence against Aging and Acne

Objectives

This study centers on the development and assessment of a facial serum fortified with the innate antioxidant’s resveratrol and quercetin, to address skin aging and acne.

Materials and Methods

The serum was carefully formulated by combining oils and ethanol, resulting in a stable biphasic emulsion with a smooth and uniform texture and a slightly acidic pH of 5.3, making it ideal for everyday application. The serum's small particle size at the nanoscale and quick absorption greatly improves its capacity to effectively target and treat fine lines, wrinkles, and acne.

Results

The antimicrobial tests showed notable efficacy against Staphylococcus aureus and Pseudomonas sp., indicating that the serum has the potential to be a skincare product with dual functions. Additionally, the serum was shown to have potent antioxidant properties as demonstrated by the DPPH and H₂O₂ scavenging tests. These tests confirmed that the serum provides robust protection against oxidative stress, a key contributor to skin aging.

Conclusion

Although the antioxidant activity of resveratrol and quercetin is slightly lower than that of ascorbic acid, their combined action effectively protects against reactive oxygen species, supporting the serum's ability to preserve youthful and healthy skin. The findings indicate that the RQ face serum has potential as a versatile skincare product, effectively targeting both signs of aging and acne, while also protecting against oxidative damage to the skin.