Volume 16

Volume 16, Issue 2

Original Article
Exploring Natural Bioactive Compounds for Radiation Countermeasure Properties: A Review
Toijam Sanjeev Lyngdoh, Dollyca Ningombam, Thangal Yumnamcha, Maibam Damayanti Devi
Vol. 16 · Issue 2 · pp. 1–9
https://doi.org/10.5530/ijpi.20260019
Original Article
Exploring the Historical Dissemination and Contemporary Resurgence of Monkeypox: A Comprehensive Examination of its Evolution, Global Impact, and Treatment Approaches
Madiha Sultana, Tushar Verma, Anju Jose, Swetha Ramesh, Sonia Singh
Vol. 16 · Issue 2 · pp. 1–9
https://doi.org/10.5530/ijpi.20260028
Original Article
Evaluation of Myostaal SB in Osteopenia Management through Bone Remineralization: A Proof-of-Concept, Open-Label, Single-Arm Study in Middle-Aged and Older Adults
Mrudul Chitrakar, Mahesh Kumar Harit, Mukesh Chawda, Megha Nalawade, Vinay Pawar, Vedvati Bhapkar
Vol. 16 · Issue 2 · pp. 1–10
https://doi.org/10.5530/ijpi.20260038
Original Article
Novel Pyrimidine Derivatives: Microwave-Assisted Synthesis and Computational Insights Toward Anti-Inflammatory Activity
Vinayak Madhukar Gaware, Kiran Bhausaheb Dhamak, Vikas Damu Kunde, Mayur Trimbak Gaikar
Vol. 16 · Issue 2 · pp. 1–10
https://doi.org/10.5530/ijpi.20260056
Original Article
Advances in Pulsatile Drug Delivery System: A Promising Strategy for Tailored Therapeutics in Modern Medicine- Review
Vuyyala Himachand, Tummadapu Bhavya, Uyyuri Kusuma, Prathi Sriya, Ravilisetty Pranavi, Nagineni Sudarshan Rao
Vol. 16 · Issue 2 · pp. 1–10
https://doi.org/10.5530/ijpi.20260159
Original Article
Engineering Smart Stimuli-Responsive Carriers for Precision Drug Delivery: Current Trends and Future Outlook
Yash Manoj Salve, Sukeshini Bharat Lote, Mayur Rajeshwar Dandekar, Isha Anil Mirzapure
Vol. 16 · Issue 2 · pp. 1–12
https://doi.org/10.5530/ijpi.20260507
Original Article
Formulation and Evaluation of Clindamycin Loaded Biodegradable Dental Cones for Sustained Drug Release in Post-Extraction Management
M Pradeep Kumar, E Ganga Prasanna, M Mahesh Yadav, B Jagadeesh Babu, C. Manjula, Pranav B Patil, Samarth Santosh Londhe, Suraj Ram Mashale, Rohan Ravsaheb Latwade
Vol. 16 · Issue 2 · pp. 1–9
https://doi.org/10.5530/ijpi.20260527
Original Article
Branded Versus Generic Antiepileptic Drugs in Epilepsy: Weighing Clinical Impact and Cost Effectiveness
Sandeep Kumar Yadav, Pratiksha Nagesh Kini, AnilKumar Kusnoor, Mujammil Mulla, Satish Karoli, Manjula Gudhoor
Vol. 16 · Issue 2 · pp. 1–7
https://doi.org/10.5530/ijpi.20260550
Original Article
Unveiling Healthcare Professionals' Insights via Knowledge, Attitude and Practice on Materiovigilance: A Multi-Centric Prospective Interventional Study
Sameer Mahabasha, Shashikala Wali, Mandati Santhosh Reddy
Vol. 16 · Issue 2 · pp. 1–7
https://doi.org/10.5530/ijpi.20260552
Original Article
From Seizure Control to Parasite Management: Antiepileptic Drugs and Neurocysticercosis
Abhishek Pete Nagaraj, Purushotham Karadigere Nagaraju, Thoppalada Yunus Pasha
Vol. 16 · Issue 2 · pp. 1–8
https://doi.org/10.5530/ijpi.20260556
Original Article
Cheminformatics-Based Evaluation of Drug-Likeness in Selected Phytochemicals from Vateria indica (Sarjarasa)
Rajeshwari Vijaykumar Kamat, Srivarshini Srinivasan, Asath Bharathy Parasuraman
Vol. 16 · Issue 2 · pp. 1–8
https://doi.org/10.5530/ijpi.20260570
Original Article
Preclinical Models of Hepatic Injury: A Comprehensive Review of Chemically, Immunologically, and Pharmacologically Induced Liver Damage in Rat Models
Lokeshvar Ravikumar, Ramaiyan Velmurugan, Grandhi Surendra, P Sivasubramanian, Konatham Teja Kumar Reddy, Kanaka Durga Hanumanthu, R Venkateswararao, Dhanush Bellapu, Ramenani Hari Babu, Medishetti Swetha
Vol. 16 · Issue 2 · pp. 1–18
https://doi.org/10.5530/ijpi.20260603
Review Article
Neuroprotection in Parkinson’s Disease: No More Status Quo
Mary Brenda Ogwang, Deepak Kumar Jha, Sandipan Chatterjee
Vol. 16 · Issue 2 · pp. 371–383
https://doi.org/10.5530/ijpi.20260022
review Article
Integrating Molecular Modeling, Cheminformatics, and High-Throughput Screening: Paving the Way for the Future of Drug Discovery
Vaishnavi N. Thute, Sukeshini Lote
Vol. 16 · Issue 2 · pp. 384–397
https://doi.org/10.5530/ijpi.20260274
Review Article
A Review on Wasp Venom as a Chemotherapeutic Agent in Different Types of Cancer
Arige Sirisha, Rama Rao Vadapalli, Penmatsa Srinidhi, Bathula Mahalakshmi, Muchakarla Sri Yagna, Kanuri Teja, T. Sowmya Sri
Vol. 16 · Issue 2 · pp. 398–404
https://doi.org/10.5530/ijpi.20260341
Review Article
The Multifaceted Potential of Tirzepatide in Metabolic and Non-Metabolic Disorders
Thalal Mohamed, Srimathi Mahadevan, Jayashri Vidya Prabhakaran, Sundari Venkatesan, Mohammed Fayaz, Vijayakumar Thangavel Mahalingam
Vol. 16 · Issue 2 · pp. 405–413
https://doi.org/10.5530/ijpi.20260349
Review Article
Microplastic Pollution: The Escalating Environmental and Health Hazards Threatening Ecosystems and Human Well-being
Harshith Naganna, Kumble Prakash Rao Tejas Rao, Tejaswi Hiremarali Lokanathan, Mathada Vamadevaiah Ravishankar
Vol. 16 · Issue 2 · pp. 414–424
https://doi.org/10.5530/ijpi.20260360
Review Article
Mouth Dissolving Tablets: Bridging Laboratory Innovations and Consumer Convenience
Kirtimaya Mishra, Asra Jabeen, Swetha Vegesna, Gowri Sankar Chintapalli, Debasis Patra, Diptimayee Jena
Vol. 16 · Issue 2 · pp. 425–430
https://doi.org/10.5530/ijpi.20260373
Review Article
A Brief Review of Drug Delivery System Used in Breast Cancer Therapies
Niyati Shah, Ritu Sapra, Maitry Suthar, Piyushkumar Sadhu, Nisha Mandloi, Mamta Kumari, Chitrali Talele, Chintan Aundhia
Vol. 16 · Issue 2 · pp. 431–441
https://doi.org/10.5530/ijpi.20260010
Review Article
Synthesis and Biomedical Applications of Titanium Dioxide Nanoparticles a Literature Review on Current Advances and Future Directions
Kalyani Andraskar, Krishna Raj, Abhay Tiwary, Poonam Lal
Vol. 16 · Issue 2 · pp. 442–449
https://doi.org/10.5530/ijpi.20260430
Review Article
Real-Time Release Testing (RTRT) in Pharmaceutical Quality Control: Current Practices and Future Prospects
Mayur Rajeshwar Dandekar, Isha anil Mirzapure, Yash Manoj Salve, Deepak Khobragade
Vol. 16 · Issue 2 · pp. 450–461
https://doi.org/10.5530/ijpi.20260432
Review Article
The Role of GMP Audits in Ensuring Drug Quality and Safety in Drugs
Mayur Dandekar, Deepak khobragade, Yash Salve, Sakshi Mandhane, Isha Mirzapure
Vol. 16 · Issue 2 · pp. 462–469
https://doi.org/10.5530/ijpi.20260480
Review Article
Vaccines: A Comprehensive Review of Vaccine Evolution and mRNA Technology
Shweta Bhandari, Rahul Trivedi, Rajesh Hadia, Ajay kumar Saini, Vishal Garg, Ram Singh
Vol. 16 · Issue 2 · pp. 470–475
https://doi.org/10.5530/ijpi.20260588
Review Article
Exploiting MMR Pathways in Plasmodium as Novel Antimalarial Targets: Opportunities and Challenges
Mohammed Tarique, Ziaullah Sain, Yusuf Ahmad
Vol. 16 · Issue 2 · pp. 476–489
https://doi.org/10.5530/ijpi.20260154
Review Article
Juvenile Animal Toxicity Studies of Pharmaceuticals and Industrial Chemicals for Regulatory Preclinical Safety Assessment
Rohit Bairagi, Ruchi Suryawanshi, Suankit Harane, Milind Umekar, Vinita Kale
Vol. 16 · Issue 2 · pp. 490–499
https://doi.org/10.5530/ijpi.20260578
Review Article
L-Carnitine in Reproductive Health: A Narrative Review on Its Pharmacological Role in Enhancing Fertility Outcomes
M Varsha, Sarumathy Sundararajan
Vol. 16 · Issue 2 · pp. 500–506
https://doi.org/10.5530/ijpi.20260065
Review Article
Navigating the Landscape of OTC Drug Utilization and Regulatory Challenges in India: Insights Review
Blessy K George, Jaidev Kumar, Sunil Kumar, Balakeshaw Ramaiah
Vol. 16 · Issue 2 · pp. 507–516
https://doi.org/10.5530/ijpi.20260514
Review Article
Metabolism of mRNA Therapeutics: Insights into Pharmacokinetics and Toxicology
Yogita Shinde, Tanishka Prakash Sharma, Archana Shaha, Rakesh Chaudhari, Rashmi Rajeghorpade, Dipali Talele, Chitrali Talele
Vol. 16 · Issue 2 · pp. 517–522
https://doi.org/10.5530/ijpi.20260539
Review Article
Cancer Stem Cells in Breast Cancer: Unlocking New Frontiers in Therapeutic Strategies
Qamre Alam, Reem Saeed Alazragi, Alaa Al-Kathiri, Alrayan Abass Albaz, Jawaher Mohammad Alshehri, Fatimah Ali Alsaffar, Dalia Alammari, Saleh Alqahtani
Vol. 16 · Issue 2 · pp. 523–535
https://doi.org/10.5530/ijpi.20260153
Review Article
The Impact of Nanoparticulate Drug Delivery Systems on Cancer Therapy and the Role of Artificial Intelligence
Santosh Kumar Dash, Ashutosh Padhan, Abdul Sayeed Khan, Tusara Kanta Behera, Sachhidananda Mohapatra, Sulagna Parta, Ranjan Kumar Sahoo
Vol. 16 · Issue 2 · pp. 536–540
https://doi.org/10.5530/ijpi.20260109
Review Article
Gene Editing Frontiers: CRISPR-Cas9 as a Novel Therapeutic Approach for Autism Spectrum Disorder
Arya Deshmukh, Mujibullah Sheikh, Akanksha Dange
Vol. 16 · Issue 2 · pp. 541–560
https://doi.org/10.5530/ijpi.20260081
Review Article
Chiral Switch in Antidepressants: A New Frontier for Safer and More Effective Personalized Therapies: A Review
Nandula Lavanya, Rashmi Nelligare Gopalakrishna
Vol. 16 · Issue 2 · pp. 561–568
https://doi.org/10.5530/ijpi.20260469
Original Article
Formulation, Optimization, and Evaluation of Lornoxicam Medicated Chewing Gum Using Ion Exchange Resin Taste Masking
Kinjal Shah, Hemani Joshi, Shailvi Shah, Tejal Mehta
Vol. 16 · Issue 2 · pp. 596–578
https://doi.org/10.5530/ijpi.20260096
Original Article
Modulating Metabolic and Cardiovascular Adverse Effects of Olanzapine with Theobroma cocoa a Preclinical Insight into Synergistic Cardioprotection
Varsha Aniket Patole, Santosh Bhausaheb Dighe, Sapna Baban Khemnar, Gaurao subhash damare, Vaibhav vitthal bhone, Shweta Shantaram Jadhav
Vol. 16 · Issue 2 · pp. 579–584
https://doi.org/10.5530/ijpi.20260113
Original Article
Screening of Phytochemicals as PIP5K1α Protein Inhibitors for Breast Cancer Treatment: A Bio Computational Study
Ahmed Mulfi Alharbi
Vol. 16 · Issue 2 · pp. 585–589
https://doi.org/10.5530/ijpi.20260049
Original Article
Drug Utilization Evaluation of Proton Pump Inhibitors in the General Medicine Ward of a Tertiary Care Hospital
Shivalingayya Gadagayya Hiremath, Umesh Chaudhary, Giridhar Koratagere Sreekanth, Sai Keerthana Ravishankar, Manikanta Devaraj, Shailesh Yadav
Vol. 16 · Issue 2 · pp. 590–598
https://doi.org/10.5530/ijpi.20260331
Original Article
Drug Utilization Evaluation of Antibiotics in an Indian Hospital Setting: A Prospective Observational Study
Sanatkumar Bharamu Nyamagoud, Laxmi Bhimappa Totar, Hema Yadav, S M Shoaib Ahamed, Khandke Shruti Achyut, Vaishanavi Vanasakrithmath, R Ranjani, Tanushree R Bantanur, Chandan Ashok Naik, Shivani Mathapati, Spoorthi G Lakkannavar, K H Karthik
Vol. 16 · Issue 2 · pp. 599–605
https://doi.org/10.5530/ijpi.20260421
Original Article
Preparative Separation, Identification and Characterization of N-Acylated Impurity in Ciprofloxacin Eye Drops Formulations Using 1D and 2D NMR Techniques
Bhupinder Kumar, Raju Mudhulkar, Sreedhar Gundekari, Surbhi Tiwari, Dama Venugopala Rao, Lakki Reddy Prakash, Ramakrishna Yadav Belly, Sandeep Kumar
Vol. 16 · Issue 2 · pp. 606–617
https://doi.org/10.5530/ijpi.20260460
Original Article
In silico Analysis of 6, 6’-Dihydroxythiobinupharidine on the Enzymes Involved in Cognitive Impairment
Pranav Nayak, Mohammad Ali, DR Bharathi
Vol. 16 · Issue 2 · pp. 618–624
https://doi.org/10.5530/ijpi.20260468
Original Article
DAVID and KEGG-Based Functional Enrichment Analysis of Breast Cancer Transcriptome: Mapping ECM Remodeling and Cell Division Pathways
Akram Ahmed Aloqbi
Vol. 16 · Issue 2 · pp. 625–637
https://doi.org/10.5530/ijpi.20260075
Original Article
Neuroprotection and Oxidative Stress Reduction by Bacillus coagulans: An in vitro Comparison with Escitalopram
Usha Dhoddametikurke Siddappa, Mandara Mathighatta Suresh, Mohd Sharique Katchhi, Babiker Bashir Haroun Baraka, Shilpashree Bettadapura Muralidhar, Chinthana Handankere Basavaraju, Chakure Aditya, Jyothi Murthy, Rajamma Abburu Jayaramu
Vol. 16 · Issue 2 · pp. 638–644
https://doi.org/10.5530/ijpi.20260588
Original Article
Detection of Various Poison in Biological Sample Using High Performance Thin Layer Chromatography
Jayasutha Jayram, Jerad Suresh Ayyadurai, Jagadeesan Subramanian, Lokesh kumar Dhavanam Ramesh Babu, Mohanraj vadivelu, Naveen Raj Ravi Kumar, Silviya Jenifer John Bosco, Pravin Kumar Muthukumaresan, Sathya Samikkannu, Yashwan Babu, Raman Lakshmisundaram, Ramakrishnan Trichur Venkatakrishnan
Vol. 16 · Issue 2 · pp. 645–653
https://doi.org/10.5530/ijpi.20260608
Original Article
Computational Tool and Molecular Properties to Identify the Molecular Targets of Novel Benzimidazole Derivatives as Potential COX Inhibitors via in silico Approaches
Vinod Rajendra Tawate, Sanket Keshav Tambe, Shubham Popatrao Mankar, Nilima Mahesh Wani, Sneha Abhishek Vikhe, Manisha Dhondiram Sonawane, Rohit Jaysing Bhor
Vol. 16 · Issue 2 · pp. 654–666
https://doi.org/10.5530/ijpi.20260528
Original Article
Evaluating the Safety and Efficacy of Hydroxyurea in Adult Sickle Cell Disease: A Prospective Observational Study
Rajesh Hadia, Kular Simran, Param Bhatt, Priyanka Yadav, Sarvajeet Khare, Cyril Sajan, Varunsingh Saggu, Hemraj Singh Rajput, Jitendra Lakhani
Vol. 16 · Issue 2 · pp. 667–678
https://doi.org/10.5530/ijpi.20260007
Original Article
Formulation and Evaluation of Antiacne Emulgel Using Aloe vera
Kamaladevi Kshatriya, Shivanand Swamy Panchayya Hiremath, Jathin Subhash Kalal, Fatima Sanjeri Dasankoppa, M Mahesh Yadav, Pradeep Bhimagouda Mirje, Jayatheertha Lokapur, Arpitha Lokapur, Rohan Ravsaheb Latwade, Pranav Babasaheb Patil
Vol. 16 · Issue 2 · pp. 679–686
https://doi.org/10.5530/ijpi.20260041
Original Article
Phyllanthin Topical Formulation with Penetration Enhancers Alleviates Imiquimod-Induced Psoriasis in Rats via Modulation of Inflammatory Biomarkers and Oxidative Stress Markers
Papiya Bigoniya, Vanita Chature
Vol. 16 · Issue 2 · pp. 687–701
https://doi.org/10.5530/ijpi.20260554
Original Article
In vitro Antioxidant and Antiglycemic Effects of Malus domestica, Musa acuminata Colla, Mangifera indica, Citrus reticulata and Punica granatum Fruits Peel Extracts
C Reddy Prasad, Bibi Umeza, M Yuvaraj, A K Afzal Khan, Swapna R Nayaka, Thirunavukkarasu Jayaraman
Vol. 16 · Issue 2 · pp. 702–707
https://doi.org/10.5530/ijpi.20260059
Original Article
Cardiovascular Disease Risk Factors in Diabetics with and without Metabolic Syndrome in NAFLD Patients
Mohammad Shane Alam, Yahia Mjery, Kamal Ahmad, Yahia Ali Kaabi, Mohammad Suhail Akhter, Fakhra Jabeen, Jobran Mohammad Moshi, Alaa Ali Alhazmi, Md Intekhabul Haque, Saif Elden Babikar Abdalla, Mathkour Hazem
Vol. 16 · Issue 2 · pp. 708–714
https://doi.org/10.5530/ijpi.20260150
Original Article
Investigating the Prevalence of Pathogens and Drug Sensitivity in Catheter-Associated Urinary Tract Infections among ICU Patients: Insights from a Hospital-Based Cross-Sectional Study
Navpreet Singh Babbar, Rabinoor Singh, Arti Saini, Inderjeet Verma, Tarun Singh
Vol. 16 · Issue 2 · pp. 715–721
https://doi.org/10.5530/ijpi.20260403
Original Article
Comparison of Dermatology Life Quality Index and Skindex-16 Questionnaires in Breast Cancer Patients with Radiation Dermatitis
Rohith Kuppusamy, Keerthika Devaraj, Gayathri Thiruvengadam, Nandhakumar Kannan, Mohamed Ashik Ahamed Ibrahim, Sriniga Venkatesh, Raman Lakshmisundaram, Sindhu Selvam, Ruthresh Jaisankar, Aswin Venkadesh Ramamoorthy Renuga, Jayasutha Jayram, Satish Srinivas Kondaveeti
Vol. 16 · Issue 2 · pp. 722–727
https://doi.org/10.5530/ijpi.20260607
Original Article
Formulation and Development of Euphorbia hirta Phytosomes Capsule for Treatment of Urinary Tract Infection
Supriya Waghmare, Shreeya Belwalkar, Amir Shaikh, Sidhhi Bansode, Akancha Kumari, Pooja Deshmane, Archana Nagare, Mohini Bhawane, Nitin Salunkhe
Vol. 16 · Issue 2 · pp. 728–736
https://doi.org/10.5530/ijpi.20260344
Original Article
Prevalence of Concomitant Use of Angiotensin Converting Enzymes Inhibitors and Angiotensin Receptors Blockers: A Retrospective Study
Alhanouf Alhawiti, Mohamed TS Saleem, Ahmed Hasan Abdelazeem, Tahani Al Rahbeni
Vol. 16 · Issue 2 · pp. 737–743
https://doi.org/10.5530/ijpi.20260138
Original Article
Green Metric Based Thin-Layer Chromatography Coupled with Mass Spectrometry to Identify Degradation Products of Lumateperone in Bulk and Formulation
Minal Ghante, Jyoti Tangde, Vidhya Bhusari, Arpana Patil, Payal Parmar
Vol. 16 · Issue 2 · pp. 744–753
https://doi.org/10.5530/ijpi.20260273
Original Article
Evaluation of Potentially Inappropriate Medication Use in Elderly Patients Using Beers Criteria in Community Pharmacy
G Guru., Jagadish kakadiya, S. Lavanya
Vol. 16 · Issue 2 · pp. 754–761
https://doi.org/10.5530/ijpi.20260524
Original Article
In vitro Insights: Investigating the Cytotoxic Properties of Curcuma caesia Roxb. and Aloe vera in situ Gel
Ankita Bohra, Thirupambaram Nataraja Sundaram Uma Maheswari
Vol. 16 · Issue 2 · pp. 1–8
https://doi.org/10.5530/ijpi.20260087